TY - JOUR
T1 - Subdural to subgaleal EEG signal transmission
T2 - The role of distance, leakage and insulating affectors
AU - Duun-Henriksen, Jonas
AU - Sorensen, H.B.D.
AU - Kjaer, T.W.
AU - Madsen, R.E.
AU - Remvig, L.S.
AU - Jespersen, B.
AU - Duun-Henriksen, A.K.
AU - Thomsen, C.E.
PY - 2013/8
Y1 - 2013/8
N2 - Objective: To estimate the area of cortex affecting the extracranial EEG signal. Methods: The coherence between intra- and extracranial EEG channels were evaluated on at least 10. min of spontaneous, awake data from seven patients admitted for epilepsy surgery work up. Results: Cortical electrodes showed significant extracranial coherent signals in an area of approximately 150cm2 although the field of vision was probably only 31cm2 based on spatial averaging of intracranial channels taking into account the influence of the craniotomy and the silastic membrane of intracranial grids. Selecting the best cortical channels, it was possible to increase the coherence values compared to the single intracranial channel with highest coherence. The coherence seemed to increase linearly with an accumulation area up to 31cm2, where 50% of the maximal coherence was obtained accumulating from only 2cm2 (corresponding to one channel), and 75% when accumulating from 16cm2. Conclusion: The skull is an all frequency spatial averager but dominantly high frequency signal attenuator. Significance: An empirical assessment of the actual area of cerebral sources generating the extracranial EEG provides better opportunities for clinical electroencephalographers to determine the location of origin of particular patterns in the EEG.
AB - Objective: To estimate the area of cortex affecting the extracranial EEG signal. Methods: The coherence between intra- and extracranial EEG channels were evaluated on at least 10. min of spontaneous, awake data from seven patients admitted for epilepsy surgery work up. Results: Cortical electrodes showed significant extracranial coherent signals in an area of approximately 150cm2 although the field of vision was probably only 31cm2 based on spatial averaging of intracranial channels taking into account the influence of the craniotomy and the silastic membrane of intracranial grids. Selecting the best cortical channels, it was possible to increase the coherence values compared to the single intracranial channel with highest coherence. The coherence seemed to increase linearly with an accumulation area up to 31cm2, where 50% of the maximal coherence was obtained accumulating from only 2cm2 (corresponding to one channel), and 75% when accumulating from 16cm2. Conclusion: The skull is an all frequency spatial averager but dominantly high frequency signal attenuator. Significance: An empirical assessment of the actual area of cerebral sources generating the extracranial EEG provides better opportunities for clinical electroencephalographers to determine the location of origin of particular patterns in the EEG.
UR - http://www.scopus.com/inward/record.url?scp=84875862208&partnerID=8YFLogxK
U2 - 10.1016/j.clinph.2013.02.112
DO - 10.1016/j.clinph.2013.02.112
M3 - Journal article
C2 - 23578564
SN - 1388-2457
JO - Clinical Neurophysiology
JF - Clinical Neurophysiology
ER -