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Structure of the Cpf1 endonuclease R-loop complex after target DNA cleavage
Stefano Stella
, Pablo Alcón,
Guillermo Montoya
Protein Structure and Function Program
69
Citations (Scopus)
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Dive into the research topics of 'Structure of the Cpf1 endonuclease R-loop complex after target DNA cleavage'. Together they form a unique fingerprint.
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Keyphrases
R-loops
100%
Target DNA
100%
Protospacer Adjacent Motif
100%
Endonuclease
100%
DNA Cleavage
100%
Single-stranded DNA (ssDNA)
42%
DNA-RNA Hybrids
42%
CRISPR RNA (crRNA)
42%
Annealing
14%
Helix
14%
DNA Strands
14%
Dentate
14%
Lysine
14%
Hydrophobic Residues
14%
Targeting Mechanism
14%
DNA nuclease
14%
Flap
14%
Lysine Residue
14%
RNA-guided Endonucleases
14%
DNA Target
14%
Genome Editing
14%
Nuclease
14%
Hybrid Form
14%
DNA Unwinding
14%
Biochemistry, Genetics and Molecular Biology
CRISPR-Cas12A
100%
Francisella novicida
14%