Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System

Dennis V. Pedersen; Trine Amalie Fogh Gadeberg; Caroline Thomas; Yong Wang; Nicolas Joram; Rasmus Kjeldsen Jensen; Sofia M. M. Mazarakis; Margot Revel; Carine El Sissy; Steen V. Petersen; Kresten Lindorff-Larsen; Steffen Thiel; Nick Stub Laursen; Véronique Fremeaux-Bacchi; Gregers Rom Andersen

doi:10.3389/fimmu.2019.02007

Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System

Dennis V. Pedersen, Trine Amalie Fogh Gadeberg, Caroline Thomas, Yong Wang, Nicolas Joram, Rasmus Kjeldsen Jensen, Sofia M. M. Mazarakis, Margot Revel, Carine El Sissy, Steen V. Petersen, Kresten Lindorff-Larsen, Steffen Thiel, Nick Stub Laursen, Véronique Fremeaux-Bacchi, Gregers Rom Andersen

Biomolecular Sciences

18 Citations (Scopus)

19 Downloads (Pure)

Original language	English
Article number	2007
Journal	Frontiers in Immunology
Volume	10
Number of pages	19
ISSN	1664-3224
DOIs	https://doi.org/10.3389/fimmu.2019.02007
Publication status	Published - 2019

Keywords

complement
convertase
properdin
complement component C3
crystal structure
regulation
factor B

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10.3389/fimmu.2019.02007Licence: CC BY

Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement SystemFinal published version, 5.08 MBLicence: CC BY

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Pedersen, D. V., Gadeberg, T. A. F., Thomas, C., Wang, Y., Joram, N., Jensen, R. K., Mazarakis, S. M. M., Revel, M., El Sissy, C., Petersen, S. V., Lindorff-Larsen, K., Thiel, S., Laursen, N. S., Fremeaux-Bacchi, V., & Andersen, G. R. (2019). Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System. Frontiers in Immunology, 10, [2007]. https://doi.org/10.3389/fimmu.2019.02007

Pedersen, DV, Gadeberg, TAF, Thomas, C, Wang, Y, Joram, N, Jensen, RK, Mazarakis, SMM, Revel, M, El Sissy, C, Petersen, SV, Lindorff-Larsen, K, Thiel, S, Laursen, NS, Fremeaux-Bacchi, V & Andersen, GR 2019, 'Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System', Frontiers in Immunology, vol. 10, 2007. https://doi.org/10.3389/fimmu.2019.02007

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title = "Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System",

keywords = "complement, convertase, properdin, complement component C3, crystal structure, regulation, factor B",

author = "Pedersen, {Dennis V.} and Gadeberg, {Trine Amalie Fogh} and Caroline Thomas and Yong Wang and Nicolas Joram and Jensen, {Rasmus Kjeldsen} and Mazarakis, {Sofia M. M.} and Margot Revel and {El Sissy}, Carine and Petersen, {Steen V.} and Kresten Lindorff-Larsen and Steffen Thiel and Laursen, {Nick Stub} and V{\'e}ronique Fremeaux-Bacchi and Andersen, {Gregers Rom}",

year = "2019",

doi = "10.3389/fimmu.2019.02007",

language = "English",

volume = "10",

journal = "Frontiers in Immunology",

issn = "1664-3224",

publisher = "Frontiers Research Foundation",

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TY - JOUR

T1 - Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System

AU - Pedersen, Dennis V.

AU - Gadeberg, Trine Amalie Fogh

AU - Thomas, Caroline

AU - Wang, Yong

AU - Joram, Nicolas

AU - Jensen, Rasmus Kjeldsen

AU - Mazarakis, Sofia M. M.

AU - Revel, Margot

AU - El Sissy, Carine

AU - Petersen, Steen V.

AU - Lindorff-Larsen, Kresten

AU - Thiel, Steffen

AU - Laursen, Nick Stub

AU - Fremeaux-Bacchi, Véronique

AU - Andersen, Gregers Rom

PY - 2019

Y1 - 2019

KW - complement

KW - convertase

KW - properdin

KW - complement component C3

KW - crystal structure

KW - regulation

KW - factor B

U2 - 10.3389/fimmu.2019.02007

DO - 10.3389/fimmu.2019.02007

M3 - Journal article

C2 - 31507604

SN - 1664-3224

VL - 10

JO - Frontiers in Immunology

JF - Frontiers in Immunology

M1 - 2007

ER -

Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System

Keywords

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