Specific opsonic activity for staphylococci in peritoneal dialysis effluent during continuous ambulatory peritoneal dialysis

H Nielsen; F Espersen; A Kharazmi; S Antonsen; E Ejlersen; P Joffe; F B Pedersen

Specific opsonic activity for staphylococci in peritoneal dialysis effluent during continuous ambulatory peritoneal dialysis

H Nielsen, F Espersen, A Kharazmi, S Antonsen, E Ejlersen, P Joffe, F B Pedersen

4 Citations (Scopus)

Abstract

In a prospective study of intraperitoneal opsonins in 30 patients undergoing continuous ambulatory peritoneal dialysis (CAPD), the IgG concentration, the fibronectin concentration, the specific antistaphylococcal antibody level, and the opsonic activity against Staphylococcus epidermidis were measured in peritoneal dialysis effluent from the initiation of CAPD and monthly for 6 months. Significant correlation was found between the four assays, but the interindividual and intraindividual variations were considerable. No statistically significant correlation was observed between susceptibility of the patients to CAPD-related infectious peritonitis and any of the above-mentioned parameters of humoral defense. We conclude that at the present time it is not feasible to use these assays for the establishment of prognosis with regard to peritonitis in CAPD.

Original language	English
Journal	American Journal of Kidney Diseases
Volume	20
Issue number	4
Pages (from-to)	372-5
Number of pages	3
ISSN	0272-6386
Publication status	Published - 1992

Cite this

@article{e18c50b01fc211df8ed1000ea68e967b,

title = "Specific opsonic activity for staphylococci in peritoneal dialysis effluent during continuous ambulatory peritoneal dialysis",

abstract = "In a prospective study of intraperitoneal opsonins in 30 patients undergoing continuous ambulatory peritoneal dialysis (CAPD), the IgG concentration, the fibronectin concentration, the specific antistaphylococcal antibody level, and the opsonic activity against Staphylococcus epidermidis were measured in peritoneal dialysis effluent from the initiation of CAPD and monthly for 6 months. Significant correlation was found between the four assays, but the interindividual and intraindividual variations were considerable. No statistically significant correlation was observed between susceptibility of the patients to CAPD-related infectious peritonitis and any of the above-mentioned parameters of humoral defense. We conclude that at the present time it is not feasible to use these assays for the establishment of prognosis with regard to peritonitis in CAPD.",

author = "H Nielsen and F Espersen and A Kharazmi and S Antonsen and E Ejlersen and P Joffe and Pedersen, {F B}",

note = "Keywords: Adult; Aged; Aged, 80 and over; Antibodies, Bacterial; Female; Fibronectins; Hemodialysis Solutions; Humans; Immunoglobulin G; Longitudinal Studies; Male; Middle Aged; Opsonin Proteins; Peritoneal Dialysis, Continuous Ambulatory; Peritonitis; Prognosis; Prospective Studies; Staphylococcus epidermidis",

year = "1992",

language = "English",

volume = "20",

pages = "372--5",

journal = "American Journal of Kidney Diseases",

issn = "0272-6386",

publisher = "W.B.Saunders Co.",

number = "4",

}

TY - JOUR

T1 - Specific opsonic activity for staphylococci in peritoneal dialysis effluent during continuous ambulatory peritoneal dialysis

AU - Nielsen, H

AU - Espersen, F

AU - Kharazmi, A

AU - Antonsen, S

AU - Ejlersen, E

AU - Joffe, P

AU - Pedersen, F B

N1 - Keywords: Adult; Aged; Aged, 80 and over; Antibodies, Bacterial; Female; Fibronectins; Hemodialysis Solutions; Humans; Immunoglobulin G; Longitudinal Studies; Male; Middle Aged; Opsonin Proteins; Peritoneal Dialysis, Continuous Ambulatory; Peritonitis; Prognosis; Prospective Studies; Staphylococcus epidermidis

PY - 1992

Y1 - 1992

N2 - In a prospective study of intraperitoneal opsonins in 30 patients undergoing continuous ambulatory peritoneal dialysis (CAPD), the IgG concentration, the fibronectin concentration, the specific antistaphylococcal antibody level, and the opsonic activity against Staphylococcus epidermidis were measured in peritoneal dialysis effluent from the initiation of CAPD and monthly for 6 months. Significant correlation was found between the four assays, but the interindividual and intraindividual variations were considerable. No statistically significant correlation was observed between susceptibility of the patients to CAPD-related infectious peritonitis and any of the above-mentioned parameters of humoral defense. We conclude that at the present time it is not feasible to use these assays for the establishment of prognosis with regard to peritonitis in CAPD.

AB - In a prospective study of intraperitoneal opsonins in 30 patients undergoing continuous ambulatory peritoneal dialysis (CAPD), the IgG concentration, the fibronectin concentration, the specific antistaphylococcal antibody level, and the opsonic activity against Staphylococcus epidermidis were measured in peritoneal dialysis effluent from the initiation of CAPD and monthly for 6 months. Significant correlation was found between the four assays, but the interindividual and intraindividual variations were considerable. No statistically significant correlation was observed between susceptibility of the patients to CAPD-related infectious peritonitis and any of the above-mentioned parameters of humoral defense. We conclude that at the present time it is not feasible to use these assays for the establishment of prognosis with regard to peritonitis in CAPD.

M3 - Journal article

C2 - 1415206

SN - 0272-6386

VL - 20

SP - 372

EP - 375

JO - American Journal of Kidney Diseases

JF - American Journal of Kidney Diseases

IS - 4

ER -

Specific opsonic activity for staphylococci in peritoneal dialysis effluent during continuous ambulatory peritoneal dialysis

Abstract

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