Spatially varying Riemannian elasticity regularization: Application to thoracic CT registration in image-guided radiotherapy

Troels Bjerre; Mads Fogtmann Hansen; Marianne C Aznar; Per Martin Munck af Rosenschöld; Lena Specht; Rasmus Larsen

doi:10.1109/isbi.2012.6235782

Spatially varying Riemannian elasticity regularization: Application to thoracic CT registration in image-guided radiotherapy

Troels Bjerre, Mads Fogtmann Hansen, Marianne C Aznar, Per Martin Munck af Rosenschöld, Lena Specht, Rasmus Larsen

Abstract

For deformable registration of computed tomography (CT) scans in image guided radiation therapy (IGRT) we apply Riemannian elasticity regularization. We explore the use of spatially varying elasticity parameters to encourage bone rigidity and local tissue volume change only in the gross tumor volume (GTV) and the lungs. We evaluate the method on the point-validated 4DCT breathing thorax POPI-model and demonstrate its use and properties in registration of pre- and post-chemo CT scans for contour propagation in a Hodgkin lymphoma (HL) case showing significant tumor shrinkage. For the POPI-model we achieved a total mean target registration error (TRE) of 0.92 ± 0.49 mm. Using spatially varying regularization for the HL case, deformation was limited to the GTV and lungs.

Original language	English
Journal	International Symposium on Biomedical Imaging. Proceedings
Pages (from-to)	1224-27
ISSN	1945-7928
DOIs	https://doi.org/10.1109/isbi.2012.6235782
Publication status	Published - 2012

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title = "Spatially varying Riemannian elasticity regularization: Application to thoracic CT registration in image-guided radiotherapy",

abstract = "For deformable registration of computed tomography (CT) scans in image guided radiation therapy (IGRT) we apply Riemannian elasticity regularization. We explore the use of spatially varying elasticity parameters to encourage bone rigidity and local tissue volume change only in the gross tumor volume (GTV) and the lungs. We evaluate the method on the point-validated 4DCT breathing thorax POPI-model and demonstrate its use and properties in registration of pre- and post-chemo CT scans for contour propagation in a Hodgkin lymphoma (HL) case showing significant tumor shrinkage. For the POPI-model we achieved a total mean target registration error (TRE) of 0.92 ± 0.49 mm. Using spatially varying regularization for the HL case, deformation was limited to the GTV and lungs.",

author = "Troels Bjerre and Hansen, {Mads Fogtmann} and Aznar, {Marianne C} and {Munck af Rosensch{\"o}ld}, {Per Martin} and Lena Specht and Rasmus Larsen",

year = "2012",

doi = "10.1109/isbi.2012.6235782",

language = "English",

pages = "1224--27",

journal = "International Symposium on Biomedical Imaging. Proceedings",

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T1 - Spatially varying Riemannian elasticity regularization: Application to thoracic CT registration in image-guided radiotherapy

AU - Bjerre, Troels

AU - Hansen, Mads Fogtmann

AU - Aznar, Marianne C

AU - Munck af Rosenschöld, Per Martin

AU - Specht, Lena

AU - Larsen, Rasmus

PY - 2012

Y1 - 2012

N2 - For deformable registration of computed tomography (CT) scans in image guided radiation therapy (IGRT) we apply Riemannian elasticity regularization. We explore the use of spatially varying elasticity parameters to encourage bone rigidity and local tissue volume change only in the gross tumor volume (GTV) and the lungs. We evaluate the method on the point-validated 4DCT breathing thorax POPI-model and demonstrate its use and properties in registration of pre- and post-chemo CT scans for contour propagation in a Hodgkin lymphoma (HL) case showing significant tumor shrinkage. For the POPI-model we achieved a total mean target registration error (TRE) of 0.92 ± 0.49 mm. Using spatially varying regularization for the HL case, deformation was limited to the GTV and lungs.

AB - For deformable registration of computed tomography (CT) scans in image guided radiation therapy (IGRT) we apply Riemannian elasticity regularization. We explore the use of spatially varying elasticity parameters to encourage bone rigidity and local tissue volume change only in the gross tumor volume (GTV) and the lungs. We evaluate the method on the point-validated 4DCT breathing thorax POPI-model and demonstrate its use and properties in registration of pre- and post-chemo CT scans for contour propagation in a Hodgkin lymphoma (HL) case showing significant tumor shrinkage. For the POPI-model we achieved a total mean target registration error (TRE) of 0.92 ± 0.49 mm. Using spatially varying regularization for the HL case, deformation was limited to the GTV and lungs.

U2 - 10.1109/isbi.2012.6235782

DO - 10.1109/isbi.2012.6235782

M3 - Journal article

SN - 1945-7928

SP - 1224

EP - 1227

JO - International Symposium on Biomedical Imaging. Proceedings

JF - International Symposium on Biomedical Imaging. Proceedings

ER -

Spatially varying Riemannian elasticity regularization: Application to thoracic CT registration in image-guided radiotherapy

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