TY - JOUR
T1 - Sparse multi-scale diffeomorphic registration
T2 - the kernel bundle framework
AU - Sommer, Stefan Horst
AU - Lauze, Francois Bernard
AU - Nielsen, Mads
AU - Pennec, Xavier
PY - 2013/7
Y1 - 2013/7
N2 - In order to detect small-scale deformations during disease propagation while allowing large-scale deformation needed for inter-subject registration, we wish to model deformation at multiple scales and represent the deformation compactly at the relevant scales only. This paper presents the kernel bundle extension of the LDDMM framework that allows multiple kernels at multiple scales to be incorporated in the registration. We combine sparsity priors with the kernel bundle resulting in compact representations across scales, and we present the mathematical foundation of the framework with derivation of the KB-EPDiff evolution equations. Through examples, we illustrate the influence of the kernel scale and show that the method achieves the important property of sparsity across scales. In addition, we demonstrate on a dataset of annotated lung CT images how the kernel bundle framework with a compact representation reaches the same accuracy as the standard method optimally tuned with respect to scale.
AB - In order to detect small-scale deformations during disease propagation while allowing large-scale deformation needed for inter-subject registration, we wish to model deformation at multiple scales and represent the deformation compactly at the relevant scales only. This paper presents the kernel bundle extension of the LDDMM framework that allows multiple kernels at multiple scales to be incorporated in the registration. We combine sparsity priors with the kernel bundle resulting in compact representations across scales, and we present the mathematical foundation of the framework with derivation of the KB-EPDiff evolution equations. Through examples, we illustrate the influence of the kernel scale and show that the method achieves the important property of sparsity across scales. In addition, we demonstrate on a dataset of annotated lung CT images how the kernel bundle framework with a compact representation reaches the same accuracy as the standard method optimally tuned with respect to scale.
KW - Kernel bundle
KW - LDDKBM
KW - LDDMM
KW - Diffeomorphic registration
KW - Scale space
KW - Computational anatomy
U2 - 10.1007/s10851-012-0409-0
DO - 10.1007/s10851-012-0409-0
M3 - Journal article
SN - 0924-9907
VL - 46
SP - 292
EP - 308
JO - Journal of Mathematical Imaging and Vision
JF - Journal of Mathematical Imaging and Vision
IS - 3
ER -