Societal costs and patients' experience of health inequities before and after diagnosis of psoriatic arthritis: A Danish cohort study

Lars Erik Kristensen; Tanja S. Jørgensen; Robin Christensen; Henrik Gudbergsen; Lene Dreyer; Christine Ballegaard; Lennart T.H. Jacobsson; Vibeke Strand; Philip J. Mease; Jakob Kjellberg

doi:10.1136/annrheumdis-2016-210579

Societal costs and patients' experience of health inequities before and after diagnosis of psoriatic arthritis: A Danish cohort study

Lars Erik Kristensen^*, Tanja S. Jørgensen, Robin Christensen, Henrik Gudbergsen, Lene Dreyer, Christine Ballegaard, Lennart T.H. Jacobsson, Vibeke Strand, Philip J. Mease, Jakob Kjellberg

^*Corresponding author for this work

Department of Clinical Medicine

28 Citations (Scopus)

Abstract

Objectives To comprehensively study the comorbidities, healthcare and public transfer (allowance) costs in patients with psoriatic arthritis (PsA) before and after diagnosis. Methods Nationwide cohort study, using data from Danish registries from January 1998 through December 2014. A total of 10â 525 patients with PsA and 20â 777 matched general population comparator (GPC) subjects were included. Societal costs, employment status and occurrence of comorbidities in patients with PsA both before and after diagnosis were compared with GPC subjects. Results At baseline, patients with PsA had significantly more comorbidities, including cardiovascular disease (OR 1. 70 95% CI 1. 55 to 1. 86), respiratory diseases (OR 1. 73 95% CI 1. 54 to 1. 96) and infectious diseases (OR 2. 03 95% CI 1. 69 to 2. 42) compared with GPC subjects. At all time points, patients with PsA had higher total healthcare and public transfer costs; they also had lower income (p<0.001) and incurred a net average increased societal cost of 10â 641 per patient-year compared with GPC subjects following diagnosis. The relative risk (RR) for being on disability pension 5â years prior to PsA diagnosis was 1. 36 (95% CI 1. 24 to 1. 49) compared with GPC subjects. The RR increased to 1. 60 (95% CI 1. 49 to 1. 72) at the time of diagnosis and was 2. 69 (95% CI 2. 40 to 3. 02) 10â years after diagnosis, where 21. 8% of the patients with PsA received disability pension. Conclusions Our findings are suggestive of health inequity for patients with PsA and call for individual preventive measures and societal action.

Original language	English
Journal	Annals of the Rheumatic Diseases
Volume	76
Issue number	9
Pages (from-to)	1495-1501
Number of pages	7
ISSN	0003-4967
DOIs	https://doi.org/10.1136/annrheumdis-2016-210579
Publication status	Published - 2017

Keywords

Economic Evaluations
Epidemiology
Patient perspective
Psoriatic Arthritis

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Kristensen, L. E., Jørgensen, T. S., Christensen, R., Gudbergsen, H., Dreyer, L., Ballegaard, C., Jacobsson, L. T. H., Strand, V., Mease, P. J., & Kjellberg, J. (2017). Societal costs and patients' experience of health inequities before and after diagnosis of psoriatic arthritis: A Danish cohort study. Annals of the Rheumatic Diseases, 76(9), 1495-1501. https://doi.org/10.1136/annrheumdis-2016-210579

Societal costs and patients' experience of health inequities before and after diagnosis of psoriatic arthritis: A Danish cohort study. / Kristensen, Lars Erik; Jørgensen, Tanja S.; Christensen, Robin et al.
In: Annals of the Rheumatic Diseases, Vol. 76, No. 9, 2017, p. 1495-1501.

Research output: Contribution to journal › Journal article › Research › peer-review

Kristensen, LE, Jørgensen, TS, Christensen, R, Gudbergsen, H, Dreyer, L, Ballegaard, C, Jacobsson, LTH, Strand, V, Mease, PJ & Kjellberg, J 2017, 'Societal costs and patients' experience of health inequities before and after diagnosis of psoriatic arthritis: A Danish cohort study', Annals of the Rheumatic Diseases, vol. 76, no. 9, pp. 1495-1501. https://doi.org/10.1136/annrheumdis-2016-210579

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title = "Societal costs and patients' experience of health inequities before and after diagnosis of psoriatic arthritis: A Danish cohort study",

abstract = "Objectives To comprehensively study the comorbidities, healthcare and public transfer (allowance) costs in patients with psoriatic arthritis (PsA) before and after diagnosis. Methods Nationwide cohort study, using data from Danish registries from January 1998 through December 2014. A total of 10{\^a} 525 patients with PsA and 20{\^a} 777 matched general population comparator (GPC) subjects were included. Societal costs, employment status and occurrence of comorbidities in patients with PsA both before and after diagnosis were compared with GPC subjects. Results At baseline, patients with PsA had significantly more comorbidities, including cardiovascular disease (OR 1. 70 95% CI 1. 55 to 1. 86), respiratory diseases (OR 1. 73 95% CI 1. 54 to 1. 96) and infectious diseases (OR 2. 03 95% CI 1. 69 to 2. 42) compared with GPC subjects. At all time points, patients with PsA had higher total healthcare and public transfer costs; they also had lower income (p<0.001) and incurred a net average increased societal cost of 10{\^a} 641 per patient-year compared with GPC subjects following diagnosis. The relative risk (RR) for being on disability pension 5{\^a} years prior to PsA diagnosis was 1. 36 (95% CI 1. 24 to 1. 49) compared with GPC subjects. The RR increased to 1. 60 (95% CI 1. 49 to 1. 72) at the time of diagnosis and was 2. 69 (95% CI 2. 40 to 3. 02) 10{\^a} years after diagnosis, where 21. 8% of the patients with PsA received disability pension. Conclusions Our findings are suggestive of health inequity for patients with PsA and call for individual preventive measures and societal action.",

keywords = "Economic Evaluations, Epidemiology, Patient perspective, Psoriatic Arthritis",

author = "Kristensen, {Lars Erik} and J{\o}rgensen, {Tanja S.} and Robin Christensen and Henrik Gudbergsen and Lene Dreyer and Christine Ballegaard and Jacobsson, {Lennart T.H.} and Vibeke Strand and Mease, {Philip J.} and Jakob Kjellberg",

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doi = "10.1136/annrheumdis-2016-210579",

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T1 - Societal costs and patients' experience of health inequities before and after diagnosis of psoriatic arthritis

T2 - A Danish cohort study

AU - Kristensen, Lars Erik

AU - Jørgensen, Tanja S.

AU - Christensen, Robin

AU - Gudbergsen, Henrik

AU - Dreyer, Lene

AU - Ballegaard, Christine

AU - Jacobsson, Lennart T.H.

AU - Strand, Vibeke

AU - Mease, Philip J.

AU - Kjellberg, Jakob

PY - 2017

Y1 - 2017

N2 - Objectives To comprehensively study the comorbidities, healthcare and public transfer (allowance) costs in patients with psoriatic arthritis (PsA) before and after diagnosis. Methods Nationwide cohort study, using data from Danish registries from January 1998 through December 2014. A total of 10â 525 patients with PsA and 20â 777 matched general population comparator (GPC) subjects were included. Societal costs, employment status and occurrence of comorbidities in patients with PsA both before and after diagnosis were compared with GPC subjects. Results At baseline, patients with PsA had significantly more comorbidities, including cardiovascular disease (OR 1. 70 95% CI 1. 55 to 1. 86), respiratory diseases (OR 1. 73 95% CI 1. 54 to 1. 96) and infectious diseases (OR 2. 03 95% CI 1. 69 to 2. 42) compared with GPC subjects. At all time points, patients with PsA had higher total healthcare and public transfer costs; they also had lower income (p<0.001) and incurred a net average increased societal cost of 10â 641 per patient-year compared with GPC subjects following diagnosis. The relative risk (RR) for being on disability pension 5â years prior to PsA diagnosis was 1. 36 (95% CI 1. 24 to 1. 49) compared with GPC subjects. The RR increased to 1. 60 (95% CI 1. 49 to 1. 72) at the time of diagnosis and was 2. 69 (95% CI 2. 40 to 3. 02) 10â years after diagnosis, where 21. 8% of the patients with PsA received disability pension. Conclusions Our findings are suggestive of health inequity for patients with PsA and call for individual preventive measures and societal action.

AB - Objectives To comprehensively study the comorbidities, healthcare and public transfer (allowance) costs in patients with psoriatic arthritis (PsA) before and after diagnosis. Methods Nationwide cohort study, using data from Danish registries from January 1998 through December 2014. A total of 10â 525 patients with PsA and 20â 777 matched general population comparator (GPC) subjects were included. Societal costs, employment status and occurrence of comorbidities in patients with PsA both before and after diagnosis were compared with GPC subjects. Results At baseline, patients with PsA had significantly more comorbidities, including cardiovascular disease (OR 1. 70 95% CI 1. 55 to 1. 86), respiratory diseases (OR 1. 73 95% CI 1. 54 to 1. 96) and infectious diseases (OR 2. 03 95% CI 1. 69 to 2. 42) compared with GPC subjects. At all time points, patients with PsA had higher total healthcare and public transfer costs; they also had lower income (p<0.001) and incurred a net average increased societal cost of 10â 641 per patient-year compared with GPC subjects following diagnosis. The relative risk (RR) for being on disability pension 5â years prior to PsA diagnosis was 1. 36 (95% CI 1. 24 to 1. 49) compared with GPC subjects. The RR increased to 1. 60 (95% CI 1. 49 to 1. 72) at the time of diagnosis and was 2. 69 (95% CI 2. 40 to 3. 02) 10â years after diagnosis, where 21. 8% of the patients with PsA received disability pension. Conclusions Our findings are suggestive of health inequity for patients with PsA and call for individual preventive measures and societal action.

KW - Economic Evaluations

KW - Epidemiology

KW - Patient perspective

KW - Psoriatic Arthritis

U2 - 10.1136/annrheumdis-2016-210579

DO - 10.1136/annrheumdis-2016-210579

M3 - Journal article

C2 - 28137915

AN - SCOPUS:85011955332

SN - 0003-4967

VL - 76

SP - 1495

EP - 1501

JO - Annals of the Rheumatic Diseases

JF - Annals of the Rheumatic Diseases

IS - 9

ER -

Societal costs and patients' experience of health inequities before and after diagnosis of psoriatic arthritis: A Danish cohort study

Abstract

Keywords

UN SDGs

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