SNARE complexes prepare for membrane fusion

Jakob B Sørensen

doi:10.1016/j.tins.2005.06.007

SNARE complexes prepare for membrane fusion

76 Citations (Scopus)

Abstract

According to a popular theory, the three presynaptic SNARE proteins (syntaxin 1, synaptobrevin 2 and SNAP-25) drive neuroexocytosis by forming a complex that forces vesicle and plasma membranes together. However, individual reactions in this process have been difficult to resolve. Now, two groups have succeeded in studying a very early and a very late step in the fusion process.

Original language	English
Journal	TINS - Trends in Neurosciences
Volume	28
Issue number	9
Pages (from-to)	453-5
Number of pages	2
ISSN	0166-2236
DOIs	https://doi.org/10.1016/j.tins.2005.06.007
Publication status	Published - 2005
Externally published	Yes

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10.1016/j.tins.2005.06.007

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title = "SNARE complexes prepare for membrane fusion",

abstract = "According to a popular theory, the three presynaptic SNARE proteins (syntaxin 1, synaptobrevin 2 and SNAP-25) drive neuroexocytosis by forming a complex that forces vesicle and plasma membranes together. However, individual reactions in this process have been difficult to resolve. Now, two groups have succeeded in studying a very early and a very late step in the fusion process.",

author = "S{\o}rensen, {Jakob B}",

note = "Keywords: Animals; Exocytosis; Humans; Membrane Fusion; Neurons; SNARE Proteins; Synaptic Membranes; Synaptic Vesicles; Syntaxin 1; Vesicular Transport Proteins",

year = "2005",

doi = "10.1016/j.tins.2005.06.007",

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TY - JOUR

T1 - SNARE complexes prepare for membrane fusion

AU - Sørensen, Jakob B

N1 - Keywords: Animals; Exocytosis; Humans; Membrane Fusion; Neurons; SNARE Proteins; Synaptic Membranes; Synaptic Vesicles; Syntaxin 1; Vesicular Transport Proteins

PY - 2005

Y1 - 2005

N2 - According to a popular theory, the three presynaptic SNARE proteins (syntaxin 1, synaptobrevin 2 and SNAP-25) drive neuroexocytosis by forming a complex that forces vesicle and plasma membranes together. However, individual reactions in this process have been difficult to resolve. Now, two groups have succeeded in studying a very early and a very late step in the fusion process.

AB - According to a popular theory, the three presynaptic SNARE proteins (syntaxin 1, synaptobrevin 2 and SNAP-25) drive neuroexocytosis by forming a complex that forces vesicle and plasma membranes together. However, individual reactions in this process have been difficult to resolve. Now, two groups have succeeded in studying a very early and a very late step in the fusion process.

U2 - 10.1016/j.tins.2005.06.007

DO - 10.1016/j.tins.2005.06.007

M3 - Review

C2 - 15996765

SN - 0166-2236

VL - 28

SP - 453

EP - 455

JO - TINS - Trends in Neurosciences

JF - TINS - Trends in Neurosciences

IS - 9

ER -

SNARE complexes prepare for membrane fusion

Abstract

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