Smoking and pregnancy-related pelvic pain

TY - JOUR

T1 - Smoking and pregnancy-related pelvic pain

AU - Biering, K

AU - Aagaard Nohr, E

AU - Olsen, J

AU - Andersen, Anne-Marie Nybo

AU - Juhl, Mette

PY - 2010/7

Y1 - 2010/7

N2 - Objective: To investigate possible associations between smoking and pregnancy-related pelvic pain. Design: Nested case-control study. Setting: Denmark 2000-2001. Population: The Danish National Birth Cohort. Methods The women were interviewed twice in pregnancy and twice after childbirth. The first pregnancy interview provided information on smoking and possible confounding factors, whereas the first interview after birth addressed case identification. Cases (n = 2302) were defined on the basis of self-reported pelvic pain, and controls were selected among women who did not report pelvic pain (n = 2692). Logistic regression analysis was used to estimate associations between smoking and pelvic pain. Main outcome mreasue: Pregnancy-related pelvic pain. Results: Compared with non-smokers, women who smoked during pregnancy had an adjusted odds ratio of 1.2 (1.0-1.4) for overall pelvic pain, similar to women who stopped smoking in early pregnancy 1.3 (1.1-1.7). The equivalent adjusted odds ratio for severe pelvic pain was 1.2 (1.0-1.5) for smokers, and 1.5 (1.2-1.9) for women who stopped smoking. Smoking intensity, measured as number of cigarettes smoked per day, was associated with pelvic pain in a dose-response pattern. Information about smoking was collected prospectively, which makes it unlikely that differential recall alone explains the results. Conclusions: Smoking was associated with pregnancy-related pelvic pain, with a dose-response pattern between reported smoking intensity and pelvic pain. These findings suggest a possible new risk factor for a common ailment during pregnancy.

AB - Objective: To investigate possible associations between smoking and pregnancy-related pelvic pain. Design: Nested case-control study. Setting: Denmark 2000-2001. Population: The Danish National Birth Cohort. Methods The women were interviewed twice in pregnancy and twice after childbirth. The first pregnancy interview provided information on smoking and possible confounding factors, whereas the first interview after birth addressed case identification. Cases (n = 2302) were defined on the basis of self-reported pelvic pain, and controls were selected among women who did not report pelvic pain (n = 2692). Logistic regression analysis was used to estimate associations between smoking and pelvic pain. Main outcome mreasue: Pregnancy-related pelvic pain. Results: Compared with non-smokers, women who smoked during pregnancy had an adjusted odds ratio of 1.2 (1.0-1.4) for overall pelvic pain, similar to women who stopped smoking in early pregnancy 1.3 (1.1-1.7). The equivalent adjusted odds ratio for severe pelvic pain was 1.2 (1.0-1.5) for smokers, and 1.5 (1.2-1.9) for women who stopped smoking. Smoking intensity, measured as number of cigarettes smoked per day, was associated with pelvic pain in a dose-response pattern. Information about smoking was collected prospectively, which makes it unlikely that differential recall alone explains the results. Conclusions: Smoking was associated with pregnancy-related pelvic pain, with a dose-response pattern between reported smoking intensity and pelvic pain. These findings suggest a possible new risk factor for a common ailment during pregnancy.

KW - Adult

KW - Body Mass Index

KW - Case-Control Studies

KW - Female

KW - Humans

KW - Parity

KW - Pelvic Pain

KW - Pregnancy

KW - Pregnancy Complications

KW - Risk Factors

KW - Smoking

KW - Young Adult

U2 - 10.1111/j.1471-0528.2010.02591.x

DO - 10.1111/j.1471-0528.2010.02591.x

M3 - Journal article

C2 - 20545674

SN - 0140-7686

VL - 117

SP - 1019

EP - 1026

JO - British Journal of Obstetrics and Gynaecology, Supplement

JF - British Journal of Obstetrics and Gynaecology, Supplement

IS - 8

ER -