Shortened duration of untreated first episode of psychosis: changes in patient characteristics at treatment

Tor Ketil Larsen; T H McGlashan; Jan Olav Johannessen; Svein Friis; C Guldberg; U Haahr; M Horneland; I Melle; L C Moe; S Opjordsmoen; Erik Simonsen; P Vaglum

doi:10.1176/appi.ajp.158.11.1917

Shortened duration of untreated first episode of psychosis: changes in patient characteristics at treatment

Tor Ketil Larsen, T H McGlashan, Jan Olav Johannessen, Svein Friis, C Guldberg, U Haahr, M Horneland, I Melle, L C Moe, S Opjordsmoen, Erik Simonsen, P Vaglum

Department of Clinical Medicine

139 Citations (Scopus)

Abstract

OBJECTIVE: This study examined whether duration of untreated psychosis can be shortened in patients with first episodes of DSM-IV schizophrenia spectrum disorders and whether shorted duration alters patient appearance at treatment.

METHOD: Two study groups were ascertained in the same Norwegian health care sector: one from 1993-1994 with usual detection methods and one from 1997-1998 with early detection strategies that included education about psychosis.

RESULTS: Patients with early detection had a shorter median duration of untreated psychosis by 21.5 weeks than patients with usual detection. The number with psychosis was greater in the early detection group; the number with schizophrenia was less. Early detection patients had more substance abuse and were younger, better adjusted premorbidly, and less ill.

CONCLUSIONS: Early detection can shorten duration of untreated psychosis and help more patients when they are less severely ill. Given the devastation of psychosis, this is a significant treatment advance.

Original language	English
Journal	The American Journal of Psychiatry
Volume	158
Issue number	11
Pages (from-to)	1917-9
Number of pages	3
ISSN	0002-953X
DOIs	https://doi.org/10.1176/appi.ajp.158.11.1917
Publication status	Published - Nov 2001

Keywords

Adult
Antipsychotic Agents
Female
Humans
Male
Schizophrenia
Schizophrenic Psychology
Severity of Illness Index
Social Adjustment
Time Factors
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1176/appi.ajp.158.11.1917

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Larsen, T. K., McGlashan, T. H., Johannessen, J. O., Friis, S., Guldberg, C., Haahr, U., Horneland, M., Melle, I., Moe, L. C., Opjordsmoen, S., Simonsen, E., & Vaglum, P. (2001). Shortened duration of untreated first episode of psychosis: changes in patient characteristics at treatment. The American Journal of Psychiatry, 158(11), 1917-9. https://doi.org/10.1176/appi.ajp.158.11.1917

Larsen, TK, McGlashan, TH, Johannessen, JO, Friis, S, Guldberg, C, Haahr, U, Horneland, M, Melle, I, Moe, LC, Opjordsmoen, S, Simonsen, E & Vaglum, P 2001, 'Shortened duration of untreated first episode of psychosis: changes in patient characteristics at treatment', The American Journal of Psychiatry, vol. 158, no. 11, pp. 1917-9. https://doi.org/10.1176/appi.ajp.158.11.1917

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abstract = "OBJECTIVE: This study examined whether duration of untreated psychosis can be shortened in patients with first episodes of DSM-IV schizophrenia spectrum disorders and whether shorted duration alters patient appearance at treatment.METHOD: Two study groups were ascertained in the same Norwegian health care sector: one from 1993-1994 with usual detection methods and one from 1997-1998 with early detection strategies that included education about psychosis.RESULTS: Patients with early detection had a shorter median duration of untreated psychosis by 21.5 weeks than patients with usual detection. The number with psychosis was greater in the early detection group; the number with schizophrenia was less. Early detection patients had more substance abuse and were younger, better adjusted premorbidly, and less ill.CONCLUSIONS: Early detection can shorten duration of untreated psychosis and help more patients when they are less severely ill. Given the devastation of psychosis, this is a significant treatment advance.",

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AU - Larsen, Tor Ketil

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AU - Johannessen, Jan Olav

AU - Friis, Svein

AU - Guldberg, C

AU - Haahr, U

AU - Horneland, M

AU - Melle, I

AU - Moe, L C

AU - Opjordsmoen, S

AU - Simonsen, Erik

AU - Vaglum, P

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N2 - OBJECTIVE: This study examined whether duration of untreated psychosis can be shortened in patients with first episodes of DSM-IV schizophrenia spectrum disorders and whether shorted duration alters patient appearance at treatment.METHOD: Two study groups were ascertained in the same Norwegian health care sector: one from 1993-1994 with usual detection methods and one from 1997-1998 with early detection strategies that included education about psychosis.RESULTS: Patients with early detection had a shorter median duration of untreated psychosis by 21.5 weeks than patients with usual detection. The number with psychosis was greater in the early detection group; the number with schizophrenia was less. Early detection patients had more substance abuse and were younger, better adjusted premorbidly, and less ill.CONCLUSIONS: Early detection can shorten duration of untreated psychosis and help more patients when they are less severely ill. Given the devastation of psychosis, this is a significant treatment advance.

AB - OBJECTIVE: This study examined whether duration of untreated psychosis can be shortened in patients with first episodes of DSM-IV schizophrenia spectrum disorders and whether shorted duration alters patient appearance at treatment.METHOD: Two study groups were ascertained in the same Norwegian health care sector: one from 1993-1994 with usual detection methods and one from 1997-1998 with early detection strategies that included education about psychosis.RESULTS: Patients with early detection had a shorter median duration of untreated psychosis by 21.5 weeks than patients with usual detection. The number with psychosis was greater in the early detection group; the number with schizophrenia was less. Early detection patients had more substance abuse and were younger, better adjusted premorbidly, and less ill.CONCLUSIONS: Early detection can shorten duration of untreated psychosis and help more patients when they are less severely ill. Given the devastation of psychosis, this is a significant treatment advance.

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KW - Antipsychotic Agents

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KW - Humans

KW - Male

KW - Schizophrenia

KW - Schizophrenic Psychology

KW - Severity of Illness Index

KW - Social Adjustment

KW - Time Factors

KW - Journal Article

KW - Research Support, Non-U.S. Gov't

KW - Research Support, U.S. Gov't, P.H.S.

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JO - The American Journal of Psychiatry

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Shortened duration of untreated first episode of psychosis: changes in patient characteristics at treatment

Abstract

Keywords

UN SDGs

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