Shc adaptor proteins are key transducers of mitogenic signaling mediated by the G protein-coupled thrombin receptor.

Medicine & Life Sciences

• Shc Signaling Adaptor Proteins 100%
• Thrombin Receptors 79%
• Transducers 56%
• G-Protein-Coupled Receptors 56%
• Thrombin 55%
• Phosphorylation 25%
• Pertussis Toxin 21%
• Receptor Protein-Tyrosine Kinases 19%
• Protein Kinase C 17%
• Tyrosine 17%
• Muscarinic M1 Receptors 13%
• phorbol 11%
• Serine Proteases 10%
• Phorbol Esters 10%
• Mutant Proteins 9%
• Growth 9%
• GTP-Binding Proteins 9%
• Transcriptional Activation 8%
• Protein Isoforms 7%
• Phosphotransferases 7%
• Fibroblasts 6%
• Cell Proliferation 6%
• Peptides 5%
• Proteins 3%

Chemical Compounds

• Thrombin 59%
• Tyrosine 25%
• Protein 23%
• Phorbol 12%
• Parasympathomimetic Agent 11%
• Tyrosine Residue 10%
• Agent Interacting With Transmitter, Hormone or Drug Receptor 10%
• Toxin 8%
• Serine 8%
• Peptide 5%