Shared peptide binding of HLA Class I and II alleles associate with cutaneous nevirapine hypersensitivity and identify novel risk alleles

Rebecca Pavlos; Elizabeth J. McKinnon; David A. Ostrov; Bjoern Peters; Soren Buus; David Koelle; Abha Chopra; Ryan Schutte; Craig Rive; Alec Redwood; Susana Restrepo; Austin Bracey; Thomas Kaever; Paisley Myers; Ellen Speers; Stacy A. Malaker; Jeffrey Shabanowitz; Yuan Jing; Silvana Gaudieri; Donald F. Hunt; Mary Carrington; David W. Haas; Simon Mallal; Elizabeth J. Phillips

doi:10.1038/s41598-017-08876-0

Shared peptide binding of HLA Class I and II alleles associate with cutaneous nevirapine hypersensitivity and identify novel risk alleles

Rebecca Pavlos, Elizabeth J. McKinnon, David A. Ostrov, Bjoern Peters, Soren Buus, David Koelle, Abha Chopra, Ryan Schutte, Craig Rive, Alec Redwood, Susana Restrepo, Austin Bracey, Thomas Kaever, Paisley Myers, Ellen Speers, Stacy A. Malaker, Jeffrey Shabanowitz, Yuan Jing, Silvana Gaudieri, Donald F. HuntMary Carrington, David W. Haas, Simon Mallal, Elizabeth J. Phillips

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Original language	English
Article number	8653
Journal	Scientific Reports
Volume	7
Number of pages	12
ISSN	2045-2322
DOIs	https://doi.org/10.1038/s41598-017-08876-0
Publication status	Published - 1 Dec 2017

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Shared peptide binding of HLA Class I and II alleles associate with cutaneous nevirapine hypersensitivity and identify novel risk allelesFinal published version, 3.85 MBLicence: CC BY

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Pavlos, R., McKinnon, E. J., Ostrov, D. A., Peters, B., Buus, S., Koelle, D., Chopra, A., Schutte, R., Rive, C., Redwood, A., Restrepo, S., Bracey, A., Kaever, T., Myers, P., Speers, E., Malaker, S. A., Shabanowitz, J., Jing, Y., Gaudieri, S., ... Phillips, E. J. (2017). Shared peptide binding of HLA Class I and II alleles associate with cutaneous nevirapine hypersensitivity and identify novel risk alleles. Scientific Reports, 7, [8653]. https://doi.org/10.1038/s41598-017-08876-0

Pavlos, R, McKinnon, EJ, Ostrov, DA, Peters, B, Buus, S, Koelle, D, Chopra, A, Schutte, R, Rive, C, Redwood, A, Restrepo, S, Bracey, A, Kaever, T, Myers, P, Speers, E, Malaker, SA, Shabanowitz, J, Jing, Y, Gaudieri, S, Hunt, DF, Carrington, M, Haas, DW, Mallal, S & Phillips, EJ 2017, 'Shared peptide binding of HLA Class I and II alleles associate with cutaneous nevirapine hypersensitivity and identify novel risk alleles', Scientific Reports, vol. 7, 8653. https://doi.org/10.1038/s41598-017-08876-0

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title = "Shared peptide binding of HLA Class I and II alleles associate with cutaneous nevirapine hypersensitivity and identify novel risk alleles",

author = "Rebecca Pavlos and McKinnon, {Elizabeth J.} and Ostrov, {David A.} and Bjoern Peters and Soren Buus and David Koelle and Abha Chopra and Ryan Schutte and Craig Rive and Alec Redwood and Susana Restrepo and Austin Bracey and Thomas Kaever and Paisley Myers and Ellen Speers and Malaker, {Stacy A.} and Jeffrey Shabanowitz and Yuan Jing and Silvana Gaudieri and Hunt, {Donald F.} and Mary Carrington and Haas, {David W.} and Simon Mallal and Phillips, {Elizabeth J.}",

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doi = "10.1038/s41598-017-08876-0",

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T1 - Shared peptide binding of HLA Class I and II alleles associate with cutaneous nevirapine hypersensitivity and identify novel risk alleles

AU - Pavlos, Rebecca

AU - McKinnon, Elizabeth J.

AU - Ostrov, David A.

AU - Peters, Bjoern

AU - Buus, Soren

AU - Koelle, David

AU - Chopra, Abha

AU - Schutte, Ryan

AU - Rive, Craig

AU - Redwood, Alec

AU - Restrepo, Susana

AU - Bracey, Austin

AU - Kaever, Thomas

AU - Myers, Paisley

AU - Speers, Ellen

AU - Malaker, Stacy A.

AU - Shabanowitz, Jeffrey

AU - Jing, Yuan

AU - Gaudieri, Silvana

AU - Hunt, Donald F.

AU - Carrington, Mary

AU - Haas, David W.

AU - Mallal, Simon

AU - Phillips, Elizabeth J.

PY - 2017/12/1

Y1 - 2017/12/1

U2 - 10.1038/s41598-017-08876-0

DO - 10.1038/s41598-017-08876-0

M3 - Journal article

C2 - 28819312

SN - 2045-2322

VL - 7

JO - Scientific Reports

JF - Scientific Reports

M1 - 8653

ER -

Shared peptide binding of HLA Class I and II alleles associate with cutaneous nevirapine hypersensitivity and identify novel risk alleles

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