Severe Crimean-Congo haemorrhagic fever presented with massive retroperitoneal haemorrhage that recovered without antiviral treatment

Mehrnaz Asadi Gharabaghi; Sadegh Chinikar; Seyyed Mojtaba Ghiasi; Maryam Morady; Taha Ahmadinejhad; Koosha Paydary; Seyed Mojtaba Ghiasi

doi:10.1136/bcr.10.2010.3408

Severe Crimean-Congo haemorrhagic fever presented with massive retroperitoneal haemorrhage that recovered without antiviral treatment

Mehrnaz Asadi Gharabaghi, Sadegh Chinikar, Seyyed Mojtaba Ghiasi, Maryam Morady, Taha Ahmadinejhad, Koosha Paydary, Seyed Mojtaba Ghiasi

Endocrinology and Metabolism

3 Citations (Scopus)

Abstract

Crimean-Congo haemorrhagic fever (CCHF) is a tickborne viral zoonosis with up to 50% mortality in humans caused by CCHF virus belonging to the genus Nairovirus, family Bunyaviridae. The geographical distribution of CCHF cases corresponds closely with the distribution of principle tick vectors that is species of Hyaloma. The disease presents with non-specific febrile symptoms, but progress to a serious haemorrhagic syndrome that, soon after, a full blown multi organ failure may develop with prominent features of liver damage and bleeding diathesis. The authors present a case of a 39-year-old man with severe CCHF with retroperitoneal haemorrhage that recovered without ribavirin administration. The case was confirmed for CCHF by serological and molecular tests.

Original language	English
Journal	BMJ Case Reports
Volume	2011
ISSN	1757-790X
DOIs	https://doi.org/10.1136/bcr.10.2010.3408
Publication status	Published - 2011

Keywords

Abattoirs
Adult
Diagnosis, Differential
Enzyme-Linked Immunosorbent Assay
Hemorrhagic Fever, Crimean
Humans
Male
Remission, Spontaneous
Retroperitoneal Space
Reverse Transcriptase Polymerase Chain Reaction
Tomography, X-Ray Computed

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10.1136/bcr.10.2010.3408

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@article{052e83c91b4846639554affb49402641,

title = "Severe Crimean-Congo haemorrhagic fever presented with massive retroperitoneal haemorrhage that recovered without antiviral treatment",

abstract = "Crimean-Congo haemorrhagic fever (CCHF) is a tickborne viral zoonosis with up to 50% mortality in humans caused by CCHF virus belonging to the genus Nairovirus, family Bunyaviridae. The geographical distribution of CCHF cases corresponds closely with the distribution of principle tick vectors that is species of Hyaloma. The disease presents with non-specific febrile symptoms, but progress to a serious haemorrhagic syndrome that, soon after, a full blown multi organ failure may develop with prominent features of liver damage and bleeding diathesis. The authors present a case of a 39-year-old man with severe CCHF with retroperitoneal haemorrhage that recovered without ribavirin administration. The case was confirmed for CCHF by serological and molecular tests.",

keywords = "Abattoirs, Adult, Diagnosis, Differential, Enzyme-Linked Immunosorbent Assay, Hemorrhagic Fever, Crimean, Humans, Male, Remission, Spontaneous, Retroperitoneal Space, Reverse Transcriptase Polymerase Chain Reaction, Tomography, X-Ray Computed",

author = "Gharabaghi, {Mehrnaz Asadi} and Sadegh Chinikar and Ghiasi, {Seyyed Mojtaba} and Maryam Morady and Taha Ahmadinejhad and Koosha Paydary and Ghiasi, {Seyed Mojtaba}",

year = "2011",

doi = "10.1136/bcr.10.2010.3408",

language = "English",

volume = "2011",

journal = "BMJ Case Reports",

issn = "1757-790X",

publisher = "BMJ Publishing Group",

}

TY - JOUR

T1 - Severe Crimean-Congo haemorrhagic fever presented with massive retroperitoneal haemorrhage that recovered without antiviral treatment

AU - Gharabaghi, Mehrnaz Asadi

AU - Chinikar, Sadegh

AU - Ghiasi, Seyyed Mojtaba

AU - Morady, Maryam

AU - Ahmadinejhad, Taha

AU - Paydary, Koosha

AU - Ghiasi, Seyed Mojtaba

PY - 2011

Y1 - 2011

N2 - Crimean-Congo haemorrhagic fever (CCHF) is a tickborne viral zoonosis with up to 50% mortality in humans caused by CCHF virus belonging to the genus Nairovirus, family Bunyaviridae. The geographical distribution of CCHF cases corresponds closely with the distribution of principle tick vectors that is species of Hyaloma. The disease presents with non-specific febrile symptoms, but progress to a serious haemorrhagic syndrome that, soon after, a full blown multi organ failure may develop with prominent features of liver damage and bleeding diathesis. The authors present a case of a 39-year-old man with severe CCHF with retroperitoneal haemorrhage that recovered without ribavirin administration. The case was confirmed for CCHF by serological and molecular tests.

AB - Crimean-Congo haemorrhagic fever (CCHF) is a tickborne viral zoonosis with up to 50% mortality in humans caused by CCHF virus belonging to the genus Nairovirus, family Bunyaviridae. The geographical distribution of CCHF cases corresponds closely with the distribution of principle tick vectors that is species of Hyaloma. The disease presents with non-specific febrile symptoms, but progress to a serious haemorrhagic syndrome that, soon after, a full blown multi organ failure may develop with prominent features of liver damage and bleeding diathesis. The authors present a case of a 39-year-old man with severe CCHF with retroperitoneal haemorrhage that recovered without ribavirin administration. The case was confirmed for CCHF by serological and molecular tests.

KW - Abattoirs

KW - Adult

KW - Diagnosis, Differential

KW - Enzyme-Linked Immunosorbent Assay

KW - Hemorrhagic Fever, Crimean

KW - Humans

KW - Male

KW - Remission, Spontaneous

KW - Retroperitoneal Space

KW - Reverse Transcriptase Polymerase Chain Reaction

KW - Tomography, X-Ray Computed

U2 - 10.1136/bcr.10.2010.3408

DO - 10.1136/bcr.10.2010.3408

M3 - Journal article

C2 - 22678739

SN - 1757-790X

VL - 2011

JO - BMJ Case Reports

JF - BMJ Case Reports

ER -

Severe Crimean-Congo haemorrhagic fever presented with massive retroperitoneal haemorrhage that recovered without antiviral treatment

Abstract

Keywords

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