Schistosomiasis and HIV in rural Zimbabwe: efficacy of treatment of schistosomiasis in individuals with HIV coinfection

Per Kallestrup, Rutendo Zinyama, Exnevia Gomo, Anthony E Butterworth, Govert J van Dam, Jan Gerstoft, Christian Erikstrup, Henrik Ullum

    32 Citations (Scopus)

    Abstract

    There is evidence from experimental models that the praziquantel-induced clearance of schistosomiasis is dependent on the host's immune response. Consequently, human immunodeficiency virus (HIV)-related immunodeficiency may impair the effect of praziquantel treatment.
    Original languageEnglish
    JournalClinical Infectious Diseases
    Volume42
    Issue number12
    Pages (from-to)1781-9
    Number of pages9
    ISSN1058-4838
    DOIs
    Publication statusPublished - 2006

    Keywords

    • Adult
    • Anthelmintics
    • Antigens, Helminth
    • CD4 Lymphocyte Count
    • Feces
    • Female
    • HIV Infections
    • Humans
    • Male
    • Parasite Egg Count
    • Praziquantel
    • Schistosomiasis
    • Viral Load
    • Zimbabwe

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