Rygestop i graviditeten, nyfødtes størrelse og NO-syntase-aktivitet i navlesnorens endotelceller--sekundaerpublikation

Malene R Andersen; Ulf Simonsen; Niels Uldbjerg; Christian Aalkjaer; Steen Stender

Rygestop i graviditeten, nyfødtes størrelse og NO-syntase-aktivitet i navlesnorens endotelceller--sekundaerpublikation

Translated title of the contribution: Smoking cessation during pregnancy, newborn size, and NO-synthase activity in endothelial cells of the umbilical cord--secondary publication

Malene R Andersen, Ulf Simonsen, Niels Uldbjerg, Christian Aalkjaer, Steen Stender

Department of Clinical Medicine

Abstract

Newborns of smokers had a lower weight, a smaller head circumference, and were shorter than newborns of smokers and ex-smokers, who stopped smoking early in pregnancy. The activity and concentration of the enzyme which produces the vasodilator nitric oxide were 36% and 47% lower, respectively, in endothelial cells of the umbilical vein from smokers compared with that from nonsmokers and ex-smokers. The findings suggest that smoking reduces nitric oxide production in the foetal vascular bed, contributing to retarded foetal growth caused by the reduction of vasodilatory capacity.
Udgivelsesdato: 2009-Jun

Translated title of the contribution	Smoking cessation during pregnancy, newborn size, and NO-synthase activity in endothelial cells of the umbilical cord--secondary publication
Original language	Danish
Journal	Ugeskrift for læger
Volume	171
Issue number	25
Pages (from-to)	2088-91
Number of pages	4
ISSN	0041-5782
Publication status	Published - 2009

Cite this

@article{d9035690784711df928f000ea68e967b,

title = "Rygestop i graviditeten, nyf{\o}dtes st{\o}rrelse og NO-syntase-aktivitet i navlesnorens endotelceller--sekundaerpublikation",

abstract = "Newborns of smokers had a lower weight, a smaller head circumference, and were shorter than newborns of smokers and ex-smokers, who stopped smoking early in pregnancy. The activity and concentration of the enzyme which produces the vasodilator nitric oxide were 36% and 47% lower, respectively, in endothelial cells of the umbilical vein from smokers compared with that from nonsmokers and ex-smokers. The findings suggest that smoking reduces nitric oxide production in the foetal vascular bed, contributing to retarded foetal growth caused by the reduction of vasodilatory capacity. Udgivelsesdato: 2009-Jun",

author = "Andersen, {Malene R} and Ulf Simonsen and Niels Uldbjerg and Christian Aalkjaer and Steen Stender",

note = "Keywords: Adult; Birth Weight; Body Height; Endothelium, Vascular; Female; Head; Humans; Infant, Newborn; Nitric Oxide Synthase Type III; Pregnancy; Smoking Cessation; Umbilical Veins; Vasodilation; Young Adult",

year = "2009",

language = "Dansk",

volume = "171",

pages = "2088--91",

journal = "Ugeskrift for l{\ae}ger",

issn = "0041-5782",

publisher = "Almindelige Danske Laegeforening",

number = "25",

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TY - JOUR

T1 - Rygestop i graviditeten, nyfødtes størrelse og NO-syntase-aktivitet i navlesnorens endotelceller--sekundaerpublikation

AU - Andersen, Malene R

AU - Simonsen, Ulf

AU - Uldbjerg, Niels

AU - Aalkjaer, Christian

AU - Stender, Steen

N1 - Keywords: Adult; Birth Weight; Body Height; Endothelium, Vascular; Female; Head; Humans; Infant, Newborn; Nitric Oxide Synthase Type III; Pregnancy; Smoking Cessation; Umbilical Veins; Vasodilation; Young Adult

PY - 2009

Y1 - 2009

N2 - Newborns of smokers had a lower weight, a smaller head circumference, and were shorter than newborns of smokers and ex-smokers, who stopped smoking early in pregnancy. The activity and concentration of the enzyme which produces the vasodilator nitric oxide were 36% and 47% lower, respectively, in endothelial cells of the umbilical vein from smokers compared with that from nonsmokers and ex-smokers. The findings suggest that smoking reduces nitric oxide production in the foetal vascular bed, contributing to retarded foetal growth caused by the reduction of vasodilatory capacity. Udgivelsesdato: 2009-Jun

AB - Newborns of smokers had a lower weight, a smaller head circumference, and were shorter than newborns of smokers and ex-smokers, who stopped smoking early in pregnancy. The activity and concentration of the enzyme which produces the vasodilator nitric oxide were 36% and 47% lower, respectively, in endothelial cells of the umbilical vein from smokers compared with that from nonsmokers and ex-smokers. The findings suggest that smoking reduces nitric oxide production in the foetal vascular bed, contributing to retarded foetal growth caused by the reduction of vasodilatory capacity. Udgivelsesdato: 2009-Jun

M3 - Tidsskriftartikel

C2 - 19678433

SN - 0041-5782

VL - 171

SP - 2088

EP - 2091

JO - Ugeskrift for læger

JF - Ugeskrift for læger

IS - 25

ER -