Risk for highly pathogenic avian influenza H5N1 virus infection in chickens in small-scale commercial farms, in high-risk area, Bangladesh, 2008

TY - JOUR

T1 - Risk for highly pathogenic avian influenza H5N1 virus infection in chickens in small-scale commercial farms, in high-risk area, Bangladesh, 2008

AU - Biswas, P.K.

AU - Rahman, M.H.

AU - Das, A.

AU - Ahmed, S.S.U.

AU - Giasuddin, M.

AU - Christensen, Jens Peter

PY - 2011/12

Y1 - 2011/12

N2 - Small-scale commercial chicken farms (FAO-defined system 3) with poor biosecurity predominate in developing countries including Bangladesh. By enroling fifteen highly pathogenic avian influenza (HPAI) cases occurring in such farms - (February - April 2008) and 45 control farms (March-May 2008) with similar set up, we conducted a case-control study to evaluate the risk factors associated with HPAI H5N1 virus infections in chickens reared in small-scale commercial farms in a spatially high-risk area in Bangladesh. Data collected by a questionnaire from the selected farms were analysed by univariable analysis and multivariable conditional logistic regression. The risk factors independently associated were 'dead crow seen at or near farm' [odds ratio (OR) 47.4, 95% confidence interval (CI) 4.7-480.3, P=0.001], 'exchanging eggtrays with market vendors' (OR 20.4, 95% CI 1.9-225.5, P=0.014) and 'mortality seen in backyard chicken reared nearby' (OR 19.4, 95% CI 2.8-131.9, P=0.002). These observations suggest that improved biosecurity might reduce the occurrence of HPAI outbreaks in small-scale commercial farms in Bangladesh.

AB - Small-scale commercial chicken farms (FAO-defined system 3) with poor biosecurity predominate in developing countries including Bangladesh. By enroling fifteen highly pathogenic avian influenza (HPAI) cases occurring in such farms - (February - April 2008) and 45 control farms (March-May 2008) with similar set up, we conducted a case-control study to evaluate the risk factors associated with HPAI H5N1 virus infections in chickens reared in small-scale commercial farms in a spatially high-risk area in Bangladesh. Data collected by a questionnaire from the selected farms were analysed by univariable analysis and multivariable conditional logistic regression. The risk factors independently associated were 'dead crow seen at or near farm' [odds ratio (OR) 47.4, 95% confidence interval (CI) 4.7-480.3, P=0.001], 'exchanging eggtrays with market vendors' (OR 20.4, 95% CI 1.9-225.5, P=0.014) and 'mortality seen in backyard chicken reared nearby' (OR 19.4, 95% CI 2.8-131.9, P=0.002). These observations suggest that improved biosecurity might reduce the occurrence of HPAI outbreaks in small-scale commercial farms in Bangladesh.

KW - Former LIFE faculty

KW - chickens

KW - highly pathogenic avian influenza

KW - H5N1

KW - house crow

KW - risk factors

U2 - 10.1111/j.1865-1682.2011.01235.x

DO - 10.1111/j.1865-1682.2011.01235.x

M3 - Journal article

SN - 1865-1674

VL - 58

SP - 519

EP - 525

JO - Transboundary and Emerging Diseases

JF - Transboundary and Emerging Diseases

IS - 6

ER -