Rhythmic 24-hour variations of frequently used clinical biochemical parameters in healthy young males - The Bispebjerg study of diurnal variations

Henriette P Sennels; Henrik L Jørgensen; Jens Peter Gøtze; Jan Fahrenkrug

doi:10.3109/00365513.2012.662281

Rhythmic 24-hour variations of frequently used clinical biochemical parameters in healthy young males - The Bispebjerg study of diurnal variations

Henriette P Sennels, Henrik L Jørgensen, Jens Peter Gøtze, Jan Fahrenkrug

32 Citations (Scopus)

Abstract

Purpose. To evaluate the influence of time of day on the circulating concentrations of 14 frequently used clinical biochemical parameters in the Bispebjerg study of diurnal variations. Materials and methods. Venous blood samples were obtained under controlled environmental, activities and food conditions from 24 healthy young men every third hour through 24 hours, nine time points in total. At each time point, the parameters' concentrations were measured. The data were analyzed by rhythmometric statistical methods and in addition the biological variations were calculated. Results. Significant oscillation of melatonin with an amplitude (amp) of 19.84 pg/ml and a peak at 03:34 h confirmed the normal 24-hour rhythms of the participants. Potassium (p

Original language	English
Journal	Scandinavian Journal of Clinical & Laboratory Investigation
Volume	72
Issue number	4
Pages (from-to)	287-295
ISSN	0036-5513
DOIs	https://doi.org/10.3109/00365513.2012.662281
Publication status	Published - Jul 2012

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Rhythmic 24-hour variations of frequently used clinical biochemical parameters in healthy young males - The Bispebjerg study of diurnal variations. / Sennels, Henriette P; Jørgensen, Henrik L ; Gøtze, Jens Peter et al.
In: Scandinavian Journal of Clinical & Laboratory Investigation, Vol. 72, No. 4, 07.2012, p. 287-295.

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AU - Gøtze, Jens Peter

AU - Fahrenkrug, Jan

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AB - Purpose. To evaluate the influence of time of day on the circulating concentrations of 14 frequently used clinical biochemical parameters in the Bispebjerg study of diurnal variations. Materials and methods. Venous blood samples were obtained under controlled environmental, activities and food conditions from 24 healthy young men every third hour through 24 hours, nine time points in total. At each time point, the parameters' concentrations were measured. The data were analyzed by rhythmometric statistical methods and in addition the biological variations were calculated. Results. Significant oscillation of melatonin with an amplitude (amp) of 19.84 pg/ml and a peak at 03:34 h confirmed the normal 24-hour rhythms of the participants. Potassium (p

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Rhythmic 24-hour variations of frequently used clinical biochemical parameters in healthy young males - The Bispebjerg study of diurnal variations

Abstract

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