TY - BOOK
T1 - Revealing the Secrets of Colletotrichum acutatum with Special Focus on Secondary Metabolism and Population Genetics
AU - Amby, Daniel Buchvaldt
PY - 2014
Y1 - 2014
N2 - Colletotrichum acutatum is an economically important fruit rot pathogen in strawberry. At the molecular level, little is known about the infection. In my PhD study, I therefore set to comprehensively understand the interaction between C. acutatum and strawberry fruits by applying multiple omic/high-throughput methods. As a novel approach, I linked transcriptomic, metabolomics and proteomic data and suggest new fungal pathogenicity related pathways to be involved in plant - fungal interactions.
I also found that sesquiterpenoids produced by C. acutatum are important for the interaction.However, these bioactive compounds are also of interest to industry and when cultured in vitro, various sesquiterpenoids are secreted by fungus, including unknowns. In addition, I have functionally characterized the first sesquiterpene synthase (STS) of Colletotrichum sp. using yeast expression systems and multiple sesquiterpenoid products are formed by STS.Furthermore, molecular diagnostics and molecular phylogenetic analyses of herbaria specimens with Colletotrichum sp. symptoms and of isolates collected from multiple plant species, revise the history of C. acutatum in the Nordic countries.
AB - Colletotrichum acutatum is an economically important fruit rot pathogen in strawberry. At the molecular level, little is known about the infection. In my PhD study, I therefore set to comprehensively understand the interaction between C. acutatum and strawberry fruits by applying multiple omic/high-throughput methods. As a novel approach, I linked transcriptomic, metabolomics and proteomic data and suggest new fungal pathogenicity related pathways to be involved in plant - fungal interactions.
I also found that sesquiterpenoids produced by C. acutatum are important for the interaction.However, these bioactive compounds are also of interest to industry and when cultured in vitro, various sesquiterpenoids are secreted by fungus, including unknowns. In addition, I have functionally characterized the first sesquiterpene synthase (STS) of Colletotrichum sp. using yeast expression systems and multiple sesquiterpenoid products are formed by STS.Furthermore, molecular diagnostics and molecular phylogenetic analyses of herbaria specimens with Colletotrichum sp. symptoms and of isolates collected from multiple plant species, revise the history of C. acutatum in the Nordic countries.
UR - https://rex.kb.dk/primo-explore/fulldisplay?docid=KGL01009013999&context=L&vid=NUI&search_scope=KGL&tab=default_tab&lang=da_DK
M3 - Ph.D. thesis
BT - Revealing the Secrets of Colletotrichum acutatum with Special Focus on Secondary Metabolism and Population Genetics
PB - Department of Plant and Environmental Sciences, Faculty of Science, University of Copenhagen
ER -