Reproductive Endocrinology in Recurrent Pregnancy Loss

TY - JOUR

T1 - Reproductive Endocrinology in Recurrent Pregnancy Loss

AU - Krog, Maria C

AU - Nielsen, Henriette Svarre

AU - Christiansen, Ole B

AU - Kolte, Astrid M

PY - 2016/7/26

Y1 - 2016/7/26

N2 - Endocrine disruptions may be important in patients experiencing recurrent pregnancy loss (RPL). This review focuses on data available on RPL and the endocrine system to investigate relevant, and perhaps modifiable, endocrine factors of importance for the disorder. Evidence indicates that some hormones may be important as immune modulators and a better understanding of this interplay has potential for improving pregnancy outcome in RPL. To date there is a lack of consensus on the effect of endocrine treatment options in RPL and there is a strong need for large randomized-controlled trials.

AB - Endocrine disruptions may be important in patients experiencing recurrent pregnancy loss (RPL). This review focuses on data available on RPL and the endocrine system to investigate relevant, and perhaps modifiable, endocrine factors of importance for the disorder. Evidence indicates that some hormones may be important as immune modulators and a better understanding of this interplay has potential for improving pregnancy outcome in RPL. To date there is a lack of consensus on the effect of endocrine treatment options in RPL and there is a strong need for large randomized-controlled trials.

KW - Journal Article

U2 - 10.1097/GRF.0000000000000225

DO - 10.1097/GRF.0000000000000225

M3 - Review

C2 - 27403585

SN - 0009-9201

VL - 59

SP - 474

EP - 486

JO - Clinical Obstetrics and Gynecology

JF - Clinical Obstetrics and Gynecology

IS - 3

ER -