Regulating intraflagellar transport

Lotte Bang Pedersen; Søren Tvorup Christensen

doi:10.1038/ncb2569

Regulating intraflagellar transport

Lotte Bang Pedersen, Søren Tvorup Christensen

Cell Biology and Physiology

13 Citations (Scopus)

Abstract

Kinesin-2 motors mediate anterograde intraflagellar transport (IFT) of IFT particles from the ciliary base to its tip, where particles are remodelled before retrograde transport by dynein 2 motors. Bardet-Biedl syndrome (BBS) and IFT-A proteins are now implicated in regulation of IFT assembly at the ciliary base and tip.

Original language	English
Journal	Nature Cell Biology
Volume	14
Issue number	9
Pages (from-to)	904-906
Number of pages	3
ISSN	1465-7392
DOIs	https://doi.org/10.1038/ncb2569
Publication status	Published - Sept 2012

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http://www.nature.com/ncb/journal/v14/n9/full/ncb2569.html

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abstract = "Kinesin-2 motors mediate anterograde intraflagellar transport (IFT) of IFT particles from the ciliary base to its tip, where particles are remodelled before retrograde transport by dynein 2 motors. Bardet-Biedl syndrome (BBS) and IFT-A proteins are now implicated in regulation of IFT assembly at the ciliary base and tip.",

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Regulating intraflagellar transport

Abstract

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