R-banding and in situ hybridization localization of single copy genes on high resolution banded chromosomes

M Rønne; F Kirpekar; Y Shibasaki; B S Poulsen; K Kristiansen

R-banding and in situ hybridization localization of single copy genes on high resolution banded chromosomes

M Rønne, F Kirpekar, Y Shibasaki, B S Poulsen, K Kristiansen

3 Citations (Scopus)

Abstract

A method to preserve high resolution R-bands on human lymphocyte chromosomes after in situ hybridization to 3H-labelled probes and autoradiography is presented. The technique was used to re-examine the location of the known oncogene N-myc. Due to the high resolution power of the present technique, this gene could be located to subband 2p24.1 in the human karyotype.

Original language	English
Journal	Anticancer Research
Volume	10
Issue number	2A
Pages (from-to)	375-7
Number of pages	2
ISSN	0250-7005
Publication status	Published - 1990
Externally published	Yes

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Cite this

@article{f524d39013c511de8478000ea68e967b,

title = "R-banding and in situ hybridization localization of single copy genes on high resolution banded chromosomes",

abstract = "A method to preserve high resolution R-bands on human lymphocyte chromosomes after in situ hybridization to 3H-labelled probes and autoradiography is presented. The technique was used to re-examine the location of the known oncogene N-myc. Due to the high resolution power of the present technique, this gene could be located to subband 2p24.1 in the human karyotype.",

author = "M R{\o}nne and F Kirpekar and Y Shibasaki and Poulsen, {B S} and K Kristiansen",

note = "Keywords: Chromosome Banding; Chromosome Mapping; Chromosomes, Human, Pair 2; Humans; Nucleic Acid Hybridization; Oncogenes; X Chromosome",

year = "1990",

language = "English",

volume = "10",

pages = "375--7",

journal = "Anticancer Research",

issn = "0250-7005",

publisher = "International Institute of Anticancer Research",

number = "2A",

}

TY - JOUR

T1 - R-banding and in situ hybridization localization of single copy genes on high resolution banded chromosomes

AU - Rønne, M

AU - Kirpekar, F

AU - Shibasaki, Y

AU - Poulsen, B S

AU - Kristiansen, K

N1 - Keywords: Chromosome Banding; Chromosome Mapping; Chromosomes, Human, Pair 2; Humans; Nucleic Acid Hybridization; Oncogenes; X Chromosome

PY - 1990

Y1 - 1990

N2 - A method to preserve high resolution R-bands on human lymphocyte chromosomes after in situ hybridization to 3H-labelled probes and autoradiography is presented. The technique was used to re-examine the location of the known oncogene N-myc. Due to the high resolution power of the present technique, this gene could be located to subband 2p24.1 in the human karyotype.

AB - A method to preserve high resolution R-bands on human lymphocyte chromosomes after in situ hybridization to 3H-labelled probes and autoradiography is presented. The technique was used to re-examine the location of the known oncogene N-myc. Due to the high resolution power of the present technique, this gene could be located to subband 2p24.1 in the human karyotype.

M3 - Journal article

C2 - 2346311

SN - 0250-7005

VL - 10

SP - 375

EP - 377

JO - Anticancer Research

JF - Anticancer Research

IS - 2A

ER -

R-banding and in situ hybridization localization of single copy genes on high resolution banded chromosomes

Abstract

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