Pyomyositis in the upper Negro river basin, Brazilian Amazonia

Alvaro Humberto Diniz Borges, Brian Faragher, David G Lalloo

    7 Citations (Scopus)

    Abstract

    Pyomyositis remains poorly documented in tropical Latin America. We therefore performed a retrospective review of cases admitted to a hospital in the upper Negro river basin during 2002-2006. Seasonality was assessed by the cosinor model and independent predictors of outcome were identified by logistic regression. Determinants of time-to-fever resolution were analysed using Cox regression. No seasonal trend was observed (p=0.284) among 82 hospitalised patients. The disease predominated in young males and the most commonly affected part of the body was the lower limb (68 [63.5%] out of 107 lesions). Staphylococcus aureus was the only identified infecting organism (18 of 20 culture results, 90%). Complications occurred in 17 patients (20.7%) and the case fatality rate was 2.4%. Children were more likely to present with eosinophilia than adults (OR= 4.20, 95% CI 1.08-16.32, p=0.048), but no other significant differences regarding clinical presentation and outcomes were observed. The time-to-fever resolution was the only independent determinant of poor outcome (OR=1.52, 95% CI 1.22-1.92, p
    Original languageEnglish
    JournalTransactions of the Royal Society of Tropical Medicine and Hygiene
    Volume106
    Issue number9
    Pages (from-to)532-7
    Number of pages6
    ISSN0035-9203
    DOIs
    Publication statusPublished - Sept 2012

    Keywords

    • Adolescent
    • Adult
    • Age Distribution
    • Anemia
    • Anti-Bacterial Agents
    • Brazil
    • Child
    • Child, Preschool
    • Female
    • Fever
    • Humans
    • Immunocompromised Host
    • Logistic Models
    • Male
    • Pyomyositis
    • Retrospective Studies
    • Rivers
    • Seasons
    • Sex Distribution
    • Staphylococcal Infections
    • Staphylococcus aureus
    • Time Factors
    • Young Adult

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