Pulp inflammation: from the reversible pulpitis to pulp necrosis during caries progression

Lars Bjørndal; Domenico Ricucci

doi:10.1007/978-3-642-55160-4_9

Pulp inflammation: from the reversible pulpitis to pulp necrosis during caries progression

Lars Bjørndal^*, Domenico Ricucci

^*Corresponding author for this work

4 Citations (Scopus)

Abstract

The advances of pulp biology combined with detailed description of the carious lesion environment, as well as the clinical evidence of treating deep lesions, have modified the view of pulp inflammation as being the nonstopping train toward apoptosis and pulp necrosis. The dentine comprises bioactive extracellular matrix, and during carious demineralization of the dentine, there is a release of bioactive molecules which can trigger the odontoblasts being members of the first line of host defense. An update of caries pathology from reversible pulpitis to necrosis is presented. A well-defined radiographical subdivision of the profound carious lesion into deep and extreme deep may be beneficially for an improved understanding of the point of irreversibility of pulp inflammation. However, the clinical estimation of inflammation remains a challenge.

Original language	English
Title of host publication	The Dental Pulp : Biology, Pathology, and Regenerative Therapies
Editors	Michel Goldberg
Number of pages	15
Publisher	Springer
Publication date	2014
Pages	125-139
ISBN (Print)	978-3-642-55159-8
ISBN (Electronic)	978-3-642-55160-4
DOIs	https://doi.org/10.1007/978-3-642-55160-4_9
Publication status	Published - 2014

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abstract = "The advances of pulp biology combined with detailed description of the carious lesion environment, as well as the clinical evidence of treating deep lesions, have modified the view of pulp inflammation as being the nonstopping train toward apoptosis and pulp necrosis. The dentine comprises bioactive extracellular matrix, and during carious demineralization of the dentine, there is a release of bioactive molecules which can trigger the odontoblasts being members of the first line of host defense. An update of caries pathology from reversible pulpitis to necrosis is presented. A well-defined radiographical subdivision of the profound carious lesion into deep and extreme deep may be beneficially for an improved understanding of the point of irreversibility of pulp inflammation. However, the clinical estimation of inflammation remains a challenge.",

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AB - The advances of pulp biology combined with detailed description of the carious lesion environment, as well as the clinical evidence of treating deep lesions, have modified the view of pulp inflammation as being the nonstopping train toward apoptosis and pulp necrosis. The dentine comprises bioactive extracellular matrix, and during carious demineralization of the dentine, there is a release of bioactive molecules which can trigger the odontoblasts being members of the first line of host defense. An update of caries pathology from reversible pulpitis to necrosis is presented. A well-defined radiographical subdivision of the profound carious lesion into deep and extreme deep may be beneficially for an improved understanding of the point of irreversibility of pulp inflammation. However, the clinical estimation of inflammation remains a challenge.

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Pulp inflammation: from the reversible pulpitis to pulp necrosis during caries progression

Abstract

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