TY - JOUR
T1 - Psoriasis
T2 - The Life Course Approach
AU - Linder, Michael Dennis
AU - Piaserico, Stefano
AU - Augustin, Matthias
AU - Fortina, Anna Belloni
AU - Cohen, Arnon D
AU - Gieler, Uwe
AU - Jemec, Gregor B E
AU - Kimball, Alexa Boer
AU - Peserico, Andrea
AU - Sampogna, Francesca
AU - Warren, Richard B
AU - de Korte, John
PY - 2016/7
Y1 - 2016/7
N2 - Over the last decades, Life Course Research (LCR), predominantly the domain of sociology, has been increasingly applied in health research, as Life Course Epidemiology (LCE). The latter is concerned with disease patterns over time, accumulation of exposures over time, critical time periods and patterns of risk. We argue that concepts from LCR and LCE could be widely applied in dermatology, in general, and, more precisely, in the study of chronic inflammatory skin diseases, e.g. atopic eczema and psoriasis. The life course approach can generally be applied in two different ways. It may be used in the more traditional manner, in which the disease and its patterns over time are examined as the outcome vari-able. Conversely, it can examine life course as the outcome variable, which is dependent on the disease course, the treatments administered, and other physical or psychosocial environmental exposures. In dermatology, this second application of the LCR concepts is both promising and relevant because of the notable impact of chronic skin diseases on the patients' quality of life. In particular, we argue how LCR may be conducive to a better understanding of the concept of 'Cumulative Life Course Impairment', which is increasingly gaining acceptance. This approach helps identifying not only individuals at risk and particularly vulnerable patients but also critical periods for optimising interventions in order to avoid life course impairment. It also may facilitate more appropriate treatment decisions in clinical practice.
AB - Over the last decades, Life Course Research (LCR), predominantly the domain of sociology, has been increasingly applied in health research, as Life Course Epidemiology (LCE). The latter is concerned with disease patterns over time, accumulation of exposures over time, critical time periods and patterns of risk. We argue that concepts from LCR and LCE could be widely applied in dermatology, in general, and, more precisely, in the study of chronic inflammatory skin diseases, e.g. atopic eczema and psoriasis. The life course approach can generally be applied in two different ways. It may be used in the more traditional manner, in which the disease and its patterns over time are examined as the outcome vari-able. Conversely, it can examine life course as the outcome variable, which is dependent on the disease course, the treatments administered, and other physical or psychosocial environmental exposures. In dermatology, this second application of the LCR concepts is both promising and relevant because of the notable impact of chronic skin diseases on the patients' quality of life. In particular, we argue how LCR may be conducive to a better understanding of the concept of 'Cumulative Life Course Impairment', which is increasingly gaining acceptance. This approach helps identifying not only individuals at risk and particularly vulnerable patients but also critical periods for optimising interventions in order to avoid life course impairment. It also may facilitate more appropriate treatment decisions in clinical practice.
KW - Adaptation, Psychological
KW - Chronic Disease
KW - Cost of Illness
KW - Humans
KW - Life Change Events
KW - Psoriasis
KW - Quality of Life
KW - Journal Article
U2 - 10.2340/00015555-2430
DO - 10.2340/00015555-2430
M3 - Journal article
C2 - 27283774
SN - 0001-5555
VL - 96
SP - 102
EP - 108
JO - Acta Dermato-Venereologica
JF - Acta Dermato-Venereologica
IS - 217
ER -