Protein kinase C in porcine retinal arteries and neuroretina following retinal ischemia-reperfusion

Bodil Gesslein; Lotta Gustafsson; Angelica Wackenfors; Fredrik Ghosh; Malin Malmsjö

Protein kinase C in porcine retinal arteries and neuroretina following retinal ischemia-reperfusion

Bodil Gesslein, Lotta Gustafsson, Angelica Wackenfors, Fredrik Ghosh, Malin Malmsjö

Neuronal Signalling

5 Citations (Scopus)

Abstract

Identification of the intracellular signal-transduction pathways activated in retinal ischemia may be important in revealing novel pharmacological targets. To date, most studies have focused on identifying neuroprotective agents. The retinal blood vessels are key organs in circulatory failure, and this study was therefore designed to examine the retinal vasculature separately from the neuroretina.

Original language	English
Journal	Molecular Vision
Volume	15
Pages (from-to)	737-46
Number of pages	10
ISSN	1090-0535
Publication status	Published - 2009

Keywords

Animals
Blotting, Western
Fluorescent Antibody Technique
Gene Expression Regulation, Enzymologic
Myocytes, Smooth Muscle
Protein Kinase C
Protein Kinase C-alpha
RNA, Messenger
Reperfusion Injury
Retina
Retinal Artery
Reverse Transcriptase Polymerase Chain Reaction
Sus scrofa

Cite this

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title = "Protein kinase C in porcine retinal arteries and neuroretina following retinal ischemia-reperfusion",

abstract = "Identification of the intracellular signal-transduction pathways activated in retinal ischemia may be important in revealing novel pharmacological targets. To date, most studies have focused on identifying neuroprotective agents. The retinal blood vessels are key organs in circulatory failure, and this study was therefore designed to examine the retinal vasculature separately from the neuroretina.",

keywords = "Animals, Blotting, Western, Fluorescent Antibody Technique, Gene Expression Regulation, Enzymologic, Myocytes, Smooth Muscle, Protein Kinase C, Protein Kinase C-alpha, RNA, Messenger, Reperfusion Injury, Retina, Retinal Artery, Reverse Transcriptase Polymerase Chain Reaction, Sus scrofa",

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T1 - Protein kinase C in porcine retinal arteries and neuroretina following retinal ischemia-reperfusion

AU - Gesslein, Bodil

AU - Gustafsson, Lotta

AU - Wackenfors, Angelica

AU - Ghosh, Fredrik

AU - Malmsjö, Malin

PY - 2009

Y1 - 2009

N2 - Identification of the intracellular signal-transduction pathways activated in retinal ischemia may be important in revealing novel pharmacological targets. To date, most studies have focused on identifying neuroprotective agents. The retinal blood vessels are key organs in circulatory failure, and this study was therefore designed to examine the retinal vasculature separately from the neuroretina.

AB - Identification of the intracellular signal-transduction pathways activated in retinal ischemia may be important in revealing novel pharmacological targets. To date, most studies have focused on identifying neuroprotective agents. The retinal blood vessels are key organs in circulatory failure, and this study was therefore designed to examine the retinal vasculature separately from the neuroretina.

KW - Animals

KW - Blotting, Western

KW - Fluorescent Antibody Technique

KW - Gene Expression Regulation, Enzymologic

KW - Myocytes, Smooth Muscle

KW - Protein Kinase C

KW - Protein Kinase C-alpha

KW - RNA, Messenger

KW - Reperfusion Injury

KW - Retina

KW - Retinal Artery

KW - Reverse Transcriptase Polymerase Chain Reaction

KW - Sus scrofa

M3 - Journal article

C2 - 19367344

SN - 1090-0535

VL - 15

SP - 737

EP - 746

JO - Molecular Vision

JF - Molecular Vision

ER -

Protein kinase C in porcine retinal arteries and neuroretina following retinal ischemia-reperfusion

Abstract

Keywords

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