Prostate cancer: 1.5 T endo-coil dynamic contrast-enhanced MRI and MR spectroscopy--correlation with prostate biopsy and prostatectomy histopathological data

Elizaveta Chabanova; Ingegerd Balslev; Vibeke Logager; Alastair Hansen; Henrik Jakobsen; Bjarne Kromann-Andersen; Nis Norgaard; Thomas Horn; Henrik S Thomsen

doi:10.1016/j.ejrad.2010.07.004

Prostate cancer: 1.5 T endo-coil dynamic contrast-enhanced MRI and MR spectroscopy--correlation with prostate biopsy and prostatectomy histopathological data

Elizaveta Chabanova, Ingegerd Balslev, Vibeke Logager, Alastair Hansen, Henrik Jakobsen, Bjarne Kromann-Andersen, Nis Norgaard, Thomas Horn, Henrik S Thomsen

14 Citations (Scopus)

Abstract

Purpose: To investigate diagnostic accuracy of detection of prostate cancer by magnetic resonance: to evaluate the performance of T2WI, DCEMRI and CSI and to correlate the results with biopsy and radical prostatectomy histopathological data. Materials and methods: 43 patients, scheduled for radical prostatectomy, underwent prostate MR examination. Prostate cancer was identified by transrectal ultrasonographically (TRUS) guided sextant biopsy. MR examination was performed at 1.5T with an endorectal MR coil. Cancer localisation was performed on sextant-basis - for comparison between TRUS biopsy, MR techniques and histopathological findings on prostatectomy specimens. Results: Prostate cancer was identified in all 43 patients by combination of the three MR techniques. The detection of prostate cancer on sextant-basis showed sensitivity and specificity: 50% and 91% for TRUS, 72% and 55% for T2WI, 49% and 69% for DCEMRI, and 46% and 78% for CSI. Conclusion: T2WI, DCEMRI and CSI in combination can identify prostate cancer. Further development of MR technologies for these MR methods is necessary to improve the detection of the prostate cancer.

Original language	English
Journal	European Journal of Radiology
Volume	80
Issue number	2
Pages (from-to)	292-6
Number of pages	5
ISSN	0720-048X
DOIs	https://doi.org/10.1016/j.ejrad.2010.07.004
Publication status	Published - Nov 2011

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Chabanova, E., Balslev, I., Logager, V., Hansen, A., Jakobsen, H., Kromann-Andersen, B., Norgaard, N., Horn, T., & Thomsen, H. S. (2011). Prostate cancer: 1.5 T endo-coil dynamic contrast-enhanced MRI and MR spectroscopy--correlation with prostate biopsy and prostatectomy histopathological data. European Journal of Radiology, 80(2), 292-6. https://doi.org/10.1016/j.ejrad.2010.07.004

Prostate cancer: 1.5 T endo-coil dynamic contrast-enhanced MRI and MR spectroscopy--correlation with prostate biopsy and prostatectomy histopathological data. / Chabanova, Elizaveta; Balslev, Ingegerd; Logager, Vibeke et al.
In: European Journal of Radiology, Vol. 80, No. 2, 11.2011, p. 292-6.

Research output: Contribution to journal › Journal article › Research › peer-review

Chabanova, E, Balslev, I, Logager, V, Hansen, A, Jakobsen, H, Kromann-Andersen, B, Norgaard, N, Horn, T & Thomsen, HS 2011, 'Prostate cancer: 1.5 T endo-coil dynamic contrast-enhanced MRI and MR spectroscopy--correlation with prostate biopsy and prostatectomy histopathological data', European Journal of Radiology, vol. 80, no. 2, pp. 292-6. https://doi.org/10.1016/j.ejrad.2010.07.004

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title = "Prostate cancer: 1.5 T endo-coil dynamic contrast-enhanced MRI and MR spectroscopy--correlation with prostate biopsy and prostatectomy histopathological data",

abstract = "Purpose: To investigate diagnostic accuracy of detection of prostate cancer by magnetic resonance: to evaluate the performance of T2WI, DCEMRI and CSI and to correlate the results with biopsy and radical prostatectomy histopathological data. Materials and methods: 43 patients, scheduled for radical prostatectomy, underwent prostate MR examination. Prostate cancer was identified by transrectal ultrasonographically (TRUS) guided sextant biopsy. MR examination was performed at 1.5T with an endorectal MR coil. Cancer localisation was performed on sextant-basis - for comparison between TRUS biopsy, MR techniques and histopathological findings on prostatectomy specimens. Results: Prostate cancer was identified in all 43 patients by combination of the three MR techniques. The detection of prostate cancer on sextant-basis showed sensitivity and specificity: 50% and 91% for TRUS, 72% and 55% for T2WI, 49% and 69% for DCEMRI, and 46% and 78% for CSI. Conclusion: T2WI, DCEMRI and CSI in combination can identify prostate cancer. Further development of MR technologies for these MR methods is necessary to improve the detection of the prostate cancer.",

author = "Elizaveta Chabanova and Ingegerd Balslev and Vibeke Logager and Alastair Hansen and Henrik Jakobsen and Bjarne Kromann-Andersen and Nis Norgaard and Thomas Horn and Thomsen, {Henrik S}",

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doi = "10.1016/j.ejrad.2010.07.004",

language = "English",

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T1 - Prostate cancer

T2 - 1.5 T endo-coil dynamic contrast-enhanced MRI and MR spectroscopy--correlation with prostate biopsy and prostatectomy histopathological data

AU - Chabanova, Elizaveta

AU - Balslev, Ingegerd

AU - Logager, Vibeke

AU - Hansen, Alastair

AU - Jakobsen, Henrik

AU - Kromann-Andersen, Bjarne

AU - Norgaard, Nis

AU - Horn, Thomas

AU - Thomsen, Henrik S

PY - 2011/11

Y1 - 2011/11

N2 - Purpose: To investigate diagnostic accuracy of detection of prostate cancer by magnetic resonance: to evaluate the performance of T2WI, DCEMRI and CSI and to correlate the results with biopsy and radical prostatectomy histopathological data. Materials and methods: 43 patients, scheduled for radical prostatectomy, underwent prostate MR examination. Prostate cancer was identified by transrectal ultrasonographically (TRUS) guided sextant biopsy. MR examination was performed at 1.5T with an endorectal MR coil. Cancer localisation was performed on sextant-basis - for comparison between TRUS biopsy, MR techniques and histopathological findings on prostatectomy specimens. Results: Prostate cancer was identified in all 43 patients by combination of the three MR techniques. The detection of prostate cancer on sextant-basis showed sensitivity and specificity: 50% and 91% for TRUS, 72% and 55% for T2WI, 49% and 69% for DCEMRI, and 46% and 78% for CSI. Conclusion: T2WI, DCEMRI and CSI in combination can identify prostate cancer. Further development of MR technologies for these MR methods is necessary to improve the detection of the prostate cancer.

AB - Purpose: To investigate diagnostic accuracy of detection of prostate cancer by magnetic resonance: to evaluate the performance of T2WI, DCEMRI and CSI and to correlate the results with biopsy and radical prostatectomy histopathological data. Materials and methods: 43 patients, scheduled for radical prostatectomy, underwent prostate MR examination. Prostate cancer was identified by transrectal ultrasonographically (TRUS) guided sextant biopsy. MR examination was performed at 1.5T with an endorectal MR coil. Cancer localisation was performed on sextant-basis - for comparison between TRUS biopsy, MR techniques and histopathological findings on prostatectomy specimens. Results: Prostate cancer was identified in all 43 patients by combination of the three MR techniques. The detection of prostate cancer on sextant-basis showed sensitivity and specificity: 50% and 91% for TRUS, 72% and 55% for T2WI, 49% and 69% for DCEMRI, and 46% and 78% for CSI. Conclusion: T2WI, DCEMRI and CSI in combination can identify prostate cancer. Further development of MR technologies for these MR methods is necessary to improve the detection of the prostate cancer.

U2 - 10.1016/j.ejrad.2010.07.004

DO - 10.1016/j.ejrad.2010.07.004

M3 - Journal article

SN - 0720-048X

VL - 80

SP - 292

EP - 296

JO - European Journal of Radiology

JF - European Journal of Radiology

IS - 2

ER -

Prostate cancer: 1.5 T endo-coil dynamic contrast-enhanced MRI and MR spectroscopy--correlation with prostate biopsy and prostatectomy histopathological data

Abstract

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