Proliferative activity in metastatic malignant melanoma: comparison of pre-treatment and post-treatment metastases.

S K Barksdale; J B Stern; H M Haupt; H Multhaupt

Proliferative activity in metastatic malignant melanoma: comparison of pre-treatment and post-treatment metastases.

S K Barksdale, J B Stern, H M Haupt, H Multhaupt

2 Citations (Scopus)

Abstract

In this study, the proliferative activity of malignant melanoma metastases was assessed before and after isolated limb perfusion chemotherapy by quantitating AgNORs, mitoses and PCNA activity. No significant difference in either AgNOR count, mitotic activity or PCNA index was observed. We conclude that AgNOR count, mitotic activity and PCNA index were not significantly effected by isolated limb perfusion chemotherapy.

Original language	English
Journal	Journal of Cutaneous Pathology
Volume	22
Issue number	4
Pages (from-to)	354-8
Number of pages	4
ISSN	0303-6987
Publication status	Published - 1995
Externally published	Yes

Cite this

@article{90660fb05d4411dd8d9f000ea68e967b,

title = "Proliferative activity in metastatic malignant melanoma: comparison of pre-treatment and post-treatment metastases.",

abstract = "In this study, the proliferative activity of malignant melanoma metastases was assessed before and after isolated limb perfusion chemotherapy by quantitating AgNORs, mitoses and PCNA activity. No significant difference in either AgNOR count, mitotic activity or PCNA index was observed. We conclude that AgNOR count, mitotic activity and PCNA index were not significantly effected by isolated limb perfusion chemotherapy.",

author = "Barksdale, {S K} and Stern, {J B} and Haupt, {H M} and H Multhaupt",

note = "Keywords: Antineoplastic Agents; Cell Division; Extremities; Humans; Infusion Pumps, Implantable; Melanoma; Mitotic Index; Necrosis; Nucleolus Organizer Region; Postoperative Complications; Postoperative Period; Proliferating Cell Nuclear Antigen; Skin Neoplasms",

year = "1995",

language = "English",

volume = "22",

pages = "354--8",

journal = "Journal of Cutaneous Pathology",

issn = "0303-6987",

publisher = "Wiley-Blackwell",

number = "4",

}

TY - JOUR

T1 - Proliferative activity in metastatic malignant melanoma: comparison of pre-treatment and post-treatment metastases.

AU - Barksdale, S K

AU - Stern, J B

AU - Haupt, H M

AU - Multhaupt, H

N1 - Keywords: Antineoplastic Agents; Cell Division; Extremities; Humans; Infusion Pumps, Implantable; Melanoma; Mitotic Index; Necrosis; Nucleolus Organizer Region; Postoperative Complications; Postoperative Period; Proliferating Cell Nuclear Antigen; Skin Neoplasms

PY - 1995

Y1 - 1995

N2 - In this study, the proliferative activity of malignant melanoma metastases was assessed before and after isolated limb perfusion chemotherapy by quantitating AgNORs, mitoses and PCNA activity. No significant difference in either AgNOR count, mitotic activity or PCNA index was observed. We conclude that AgNOR count, mitotic activity and PCNA index were not significantly effected by isolated limb perfusion chemotherapy.

AB - In this study, the proliferative activity of malignant melanoma metastases was assessed before and after isolated limb perfusion chemotherapy by quantitating AgNORs, mitoses and PCNA activity. No significant difference in either AgNOR count, mitotic activity or PCNA index was observed. We conclude that AgNOR count, mitotic activity and PCNA index were not significantly effected by isolated limb perfusion chemotherapy.

M3 - Journal article

C2 - 7499576

SN - 0303-6987

VL - 22

SP - 354

EP - 358

JO - Journal of Cutaneous Pathology

JF - Journal of Cutaneous Pathology

IS - 4

ER -

Proliferative activity in metastatic malignant melanoma: comparison of pre-treatment and post-treatment metastases.

Abstract

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