Probing the Bioactive Conformation of an Archetypal Natural Product HDAC Inhibitor with Conformationally Homogeneous Triazole-Modified Cyclic Tetrapeptides

W. Seth Horne; Christian Adam Olsen; John M. Beierle; Ana Montero; M. Reza Ghadiri

doi:10.1002/anie.200805900

Probing the Bioactive Conformation of an Archetypal Natural Product HDAC Inhibitor with Conformationally Homogeneous Triazole-Modified Cyclic Tetrapeptides

W. Seth Horne, Christian Adam Olsen, John M. Beierle, Ana Montero, M. Reza Ghadiri

121 Citations (Scopus)

Original language	English
Journal	Angewandte Chemie International Edition
Volume	48
Issue number	26
Pages (from-to)	4718-4724
ISSN	1433-7851
DOIs	https://doi.org/10.1002/anie.200805900
Publication status	Published - 2009

Keywords

cyclic peptides
drug design
enzyme inhibitors
structure-activity relationships
triazoles

Access to Document

10.1002/anie.200805900

Cite this

Probing the Bioactive Conformation of an Archetypal Natural Product HDAC Inhibitor with Conformationally Homogeneous Triazole-Modified Cyclic Tetrapeptides. / Horne, W. Seth; Olsen, Christian Adam; Beierle, John M. et al.

In: Angewandte Chemie International Edition, Vol. 48, No. 26, 2009, p. 4718-4724.

Research output: Contribution to journal › Journal article › Research › peer-review

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