Primary testicular failure in Klinefelter's syndrome: the use of bivariate luteinizing hormone-testosterone reference charts

TY - JOUR

T1 - Primary testicular failure in Klinefelter's syndrome: the use of bivariate luteinizing hormone-testosterone reference charts

AU - Aksglaede, Lise

AU - Andersson, Anna-Maria

AU - Jørgensen, Niels

AU - Jensen, Tina Kold

AU - Carlsen, Elisabeth

AU - McLachlan, Robert I

AU - Skakkebaek, Niels E

AU - Petersen, Jørgen Holm

AU - Juul, Anders

PY - 2007/2/1

Y1 - 2007/2/1

N2 - The diagnosis of androgen deficiency is based on clinical features and confirmatory low serum testosterone levels. In early primary testicular failure, a rise in serum LH levels suggests inadequate androgen action for the individual's physiological requirements despite a serum testosterone level within the normal range. The combined evaluation of serum LH and testosterone levels in the evaluation of testicular failure has not been widely advocated.

AB - The diagnosis of androgen deficiency is based on clinical features and confirmatory low serum testosterone levels. In early primary testicular failure, a rise in serum LH levels suggests inadequate androgen action for the individual's physiological requirements despite a serum testosterone level within the normal range. The combined evaluation of serum LH and testosterone levels in the evaluation of testicular failure has not been widely advocated.

U2 - http://dx.doi.org/10.1111/j.1365-2265.2006.02722.x

DO - http://dx.doi.org/10.1111/j.1365-2265.2006.02722.x

M3 - Journal article

SN - 0300-0664

VL - 66

SP - 276

EP - 281

JO - Clinical Endocrinology

JF - Clinical Endocrinology

IS - 2

ER -