Prevention of negative symptom psychopathologies in first-episode schizophrenia: two-year effects of reducing the duration of untreated psychosis

Ingrid Melle, Tor K Larsen, Ulrik Haahr, Svein Friis, Jan O Johannesen, Stein Opjordsmoen, Bjørn R Rund, Erik Simonsen, Per Vaglum, Thomas McGlashan

142 Citations (Scopus)

Abstract

The duration of untreated psychosis (DUP)-the time from onset of psychotic symptoms to the start of adequate treatment--is consistently correlated with better course and outcome, but the mechanisms are poorly understood.
Original languageEnglish
JournalArchives of General Psychiatry
Volume65
Issue number6
Pages (from-to)634-40
Number of pages7
ISSN0003-990X
DOIs
Publication statusPublished - 2008

Keywords

  • Adult
  • Antipsychotic Agents
  • Combined Modality Therapy
  • Delusions
  • Denmark
  • Depression
  • Early Diagnosis
  • Female
  • Follow-Up Studies
  • Hallucinations
  • Humans
  • Male
  • Norway
  • Patient Care Team
  • Patient Readmission
  • Prognosis
  • Psychiatric Status Rating Scales
  • Schizophrenia
  • Schizophrenic Psychology
  • Suicide, Attempted

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