Preventing Poor Vocational Functioning in Psychosis Through Early Intervention

Wenche Ten Velden Hegelstad; Kolbjorn S Bronnick; Helene Eidsmo Barder; Julie Horgen Evensen; Ulrik Haahr; Inge Joa; Jan Olav Johannessen; Johannes Langeveld; Tor Ketil Larsen; Ingrid Melle; Stein Opjordsmoen; Bjørn Rishovd Rund; Jan Ivar Rossberg; Erik Simonsen; Per Wiggen Vaglum; Thomas H McGlashan; Svein Friis

doi:10.1176/appi.ps.201500451

Preventing Poor Vocational Functioning in Psychosis Through Early Intervention

Wenche Ten Velden Hegelstad, Kolbjorn S Bronnick, Helene Eidsmo Barder, Julie Horgen Evensen, Ulrik Haahr, Inge Joa, Jan Olav Johannessen, Johannes Langeveld, Tor Ketil Larsen, Ingrid Melle, Stein Opjordsmoen, Bjørn Rishovd Rund, Jan Ivar Rossberg, Erik Simonsen, Per Wiggen Vaglum, Thomas H McGlashan, Svein Friis

Department of Clinical Medicine

6 Citations (Scopus)

Abstract

OBJECTIVE: This study tested the hypothesis that early detection of psychosis improves long-term vocational functioning through the prevention of negative symptom development.

METHODS: Generalized estimating equations and mediation analysis were conducted to examine the association between employment and negative symptoms over ten years among patients in geographic areas characterized by usual detection (N=140) or early detection (N=141) of psychosis.

RESULTS: Improved vocational outcome after ten years among patients in the early-detection area was mediated by lower levels of negative symptoms during the first five years. Regardless of symptoms, rates of full-time employment or study were lower among patients in the usual-detection versus the early-detection area.

CONCLUSIONS: Patients from an early-detection area attained lower negative symptom levels earlier compared with patients from a usual-detection area, which seemed to have facilitated vocational careers.

Original language	English
Journal	Psychiatric Services
Volume	68
Issue number	1
Pages (from-to)	100-103
Number of pages	4
ISSN	1075-2730
DOIs	https://doi.org/10.1176/appi.ps.201500451
Publication status	Published - 1 Jan 2017

Keywords

Journal Article

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Hegelstad, W. T. V., Bronnick, K. S., Barder, H. E., Evensen, J. H., Haahr, U., Joa, I., Johannessen, J. O., Langeveld, J., Larsen, T. K., Melle, I., Opjordsmoen, S., Rund, B. R., Rossberg, J. I., Simonsen, E., Vaglum, P. W., McGlashan, T. H., & Friis, S. (2017). Preventing Poor Vocational Functioning in Psychosis Through Early Intervention. Psychiatric Services, 68(1), 100-103. https://doi.org/10.1176/appi.ps.201500451

Hegelstad, WTV, Bronnick, KS, Barder, HE, Evensen, JH, Haahr, U, Joa, I, Johannessen, JO, Langeveld, J, Larsen, TK, Melle, I, Opjordsmoen, S, Rund, BR, Rossberg, JI, Simonsen, E, Vaglum, PW, McGlashan, TH & Friis, S 2017, 'Preventing Poor Vocational Functioning in Psychosis Through Early Intervention', Psychiatric Services, vol. 68, no. 1, pp. 100-103. https://doi.org/10.1176/appi.ps.201500451

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abstract = "OBJECTIVE: This study tested the hypothesis that early detection of psychosis improves long-term vocational functioning through the prevention of negative symptom development.METHODS: Generalized estimating equations and mediation analysis were conducted to examine the association between employment and negative symptoms over ten years among patients in geographic areas characterized by usual detection (N=140) or early detection (N=141) of psychosis.RESULTS: Improved vocational outcome after ten years among patients in the early-detection area was mediated by lower levels of negative symptoms during the first five years. Regardless of symptoms, rates of full-time employment or study were lower among patients in the usual-detection versus the early-detection area.CONCLUSIONS: Patients from an early-detection area attained lower negative symptom levels earlier compared with patients from a usual-detection area, which seemed to have facilitated vocational careers.",

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AU - Hegelstad, Wenche Ten Velden

AU - Bronnick, Kolbjorn S

AU - Barder, Helene Eidsmo

AU - Evensen, Julie Horgen

AU - Haahr, Ulrik

AU - Joa, Inge

AU - Johannessen, Jan Olav

AU - Langeveld, Johannes

AU - Larsen, Tor Ketil

AU - Melle, Ingrid

AU - Opjordsmoen, Stein

AU - Rund, Bjørn Rishovd

AU - Rossberg, Jan Ivar

AU - Simonsen, Erik

AU - Vaglum, Per Wiggen

AU - McGlashan, Thomas H

AU - Friis, Svein

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N2 - OBJECTIVE: This study tested the hypothesis that early detection of psychosis improves long-term vocational functioning through the prevention of negative symptom development.METHODS: Generalized estimating equations and mediation analysis were conducted to examine the association between employment and negative symptoms over ten years among patients in geographic areas characterized by usual detection (N=140) or early detection (N=141) of psychosis.RESULTS: Improved vocational outcome after ten years among patients in the early-detection area was mediated by lower levels of negative symptoms during the first five years. Regardless of symptoms, rates of full-time employment or study were lower among patients in the usual-detection versus the early-detection area.CONCLUSIONS: Patients from an early-detection area attained lower negative symptom levels earlier compared with patients from a usual-detection area, which seemed to have facilitated vocational careers.

AB - OBJECTIVE: This study tested the hypothesis that early detection of psychosis improves long-term vocational functioning through the prevention of negative symptom development.METHODS: Generalized estimating equations and mediation analysis were conducted to examine the association between employment and negative symptoms over ten years among patients in geographic areas characterized by usual detection (N=140) or early detection (N=141) of psychosis.RESULTS: Improved vocational outcome after ten years among patients in the early-detection area was mediated by lower levels of negative symptoms during the first five years. Regardless of symptoms, rates of full-time employment or study were lower among patients in the usual-detection versus the early-detection area.CONCLUSIONS: Patients from an early-detection area attained lower negative symptom levels earlier compared with patients from a usual-detection area, which seemed to have facilitated vocational careers.

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Preventing Poor Vocational Functioning in Psychosis Through Early Intervention

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