Premotor cortex modulates somatosensory cortex during voluntary movements without proprioceptive feedback

TY - JOUR

T1 - Premotor cortex modulates somatosensory cortex during voluntary movements without proprioceptive feedback

AU - Christensen, Mark Schram

AU - Lundbye-Jensen, Jesper

AU - Geertsen, Svend Sparre

AU - Petersen, Tue Hvass

AU - Paulson, Olaf B

AU - Nielsen, Jens Bo

N1 - CURIS 2007 5200 026

PY - 2007/4/1

Y1 - 2007/4/1

N2 - Movement perception relies on sensory feedback, but the involvement of efference copies remains unclear. We investigated movements without proprioceptive feedback using ischemic nerve block during fMRI in healthy humans, and found preserved activation of the primary somatosensory cortex. This activation was associated with increased interaction with premotor cortex during voluntary movements, which demonstrates that perception of movements relies in part on predictions of sensory consequences of voluntary movements that are mediated by the premotor cortex.

AB - Movement perception relies on sensory feedback, but the involvement of efference copies remains unclear. We investigated movements without proprioceptive feedback using ischemic nerve block during fMRI in healthy humans, and found preserved activation of the primary somatosensory cortex. This activation was associated with increased interaction with premotor cortex during voluntary movements, which demonstrates that perception of movements relies in part on predictions of sensory consequences of voluntary movements that are mediated by the premotor cortex.

U2 - 10.1038/nn1873

DO - 10.1038/nn1873

M3 - Journal article

C2 - 17369825

SN - 1097-6256

VL - 10

SP - 417

EP - 419

JO - Nature Neuroscience

JF - Nature Neuroscience

IS - 4

ER -