Preferences for prenatal testing among pregnant women, partners and health professionals

Ida Charlotte Bay Lund; Naja Becher; Olav Bjørn Petersen; Melissa Hill; Lyn Chitty; Ida Vogel

Preferences for prenatal testing among pregnant women, partners and health professionals

Ida Charlotte Bay Lund, Naja Becher, Olav Bjørn Petersen, Melissa Hill, Lyn Chitty, Ida Vogel

8 Citations (Scopus)

2 Downloads (Pure)

Abstract

INTRODUCTION: Cell-free DNA testing (cfDNA testing) in maternal plasma has recently been implemented in Danish healthcare. Prior to that we wanted to evaluate the preferences among pregnant women, partners and health professionals regarding cfDNA testing compared with invasive prenatal diagnostics. METHODS: Responders were recruited at public hospitals in the Central and North Denmark Regions. Stated preferences for prenatal testing were obtained through an online questionnaire incorporating a discrete choice experiment. Test choices differed according to attributes such as risk of miscarriage (none or small) and genetic information provided by the test; simple (Down syndrome only) or comprehensive (chromosomal abnormalities beyond Down syndrome). RESULTS: No risk of miscarriage was the key attribute affecting the preferences of women (n = 315) and partners (n = 102). However, women with experiences of invasive testing placed more emphasis on comprehensive genetic information and less on risk of miscarriage compared with other women. Likewise, foetal medicine experts, obstetricians and sonographers (n = 57) had a greater preference for comprehensive genetic information than midwives who were not directly involved in counselling for prenatal testing (n = 48). CONCLUSIONS: As safety seems to affect the majority of pregnant couples’ choice behaviour, thorough pre-test counselling by trained health professionals is of paramount importance.

Original language	English
Article number	A5486
Journal	Danish Medical Journal
Volume	65
Issue number	5
Number of pages	6
ISSN	1603-9629
Publication status	Published - May 2018
Externally published	Yes

Keywords

Abortion, Spontaneous/epidemiology
Adult
Attitude of Health Personnel
Cell-Free Nucleic Acids/analysis
Choice Behavior
Counseling
Denmark
Female
Hospitals, Public
Humans
Male
Middle Aged
Patient Preference
Pregnancy
Prenatal Diagnosis/psychology
Sexual Partners/psychology
Surveys and Questionnaires

Access to Document

a5486_preferences_for_prenatal_testing_among_pregnant_women_partners_and_health_professionalsFinal published version, 158 KBLicence: CC BY-NC

http://ugeskriftet.dk/files/a5486_preferences_for_prenatal_testing_among_pregnant_women_partners_and_health_professionals.pdfLicence: CC BY-NC

Cite this

@article{c0061152cc6c4743a593cd71c07781de,

title = "Preferences for prenatal testing among pregnant women, partners and health professionals",

abstract = "INTRODUCTION: Cell-free DNA testing (cfDNA testing) in maternal plasma has recently been implemented in Danish healthcare. Prior to that we wanted to evaluate the preferences among pregnant women, partners and health professionals regarding cfDNA testing compared with invasive prenatal diagnostics. METHODS: Responders were recruited at public hospitals in the Central and North Denmark Regions. Stated preferences for prenatal testing were obtained through an online questionnaire incorporating a discrete choice experiment. Test choices differed according to attributes such as risk of miscarriage (none or small) and genetic information provided by the test; simple (Down syndrome only) or comprehensive (chromosomal abnormalities beyond Down syndrome). RESULTS: No risk of miscarriage was the key attribute affecting the preferences of women (n = 315) and partners (n = 102). However, women with experiences of invasive testing placed more emphasis on comprehensive genetic information and less on risk of miscarriage compared with other women. Likewise, foetal medicine experts, obstetricians and sonographers (n = 57) had a greater preference for comprehensive genetic information than midwives who were not directly involved in counselling for prenatal testing (n = 48). CONCLUSIONS: As safety seems to affect the majority of pregnant couples{\textquoteright} choice behaviour, thorough pre-test counselling by trained health professionals is of paramount importance.",

keywords = "Abortion, Spontaneous/epidemiology, Adult, Attitude of Health Personnel, Cell-Free Nucleic Acids/analysis, Choice Behavior, Counseling, Denmark, Female, Hospitals, Public, Humans, Male, Middle Aged, Patient Preference, Pregnancy, Prenatal Diagnosis/psychology, Sexual Partners/psychology, Surveys and Questionnaires",

author = "Lund, {Ida Charlotte Bay} and Naja Becher and Petersen, {Olav Bj{\o}rn} and Melissa Hill and Lyn Chitty and Ida Vogel",

note = "Articles published in the DMJ are “open access”. This means that the articles are distributed under the terms of the Creative Commons Attribution Non-commercial License, which permits any non-commercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.",

year = "2018",

month = may,

language = "English",

volume = "65",

journal = "Danish Medical Journal",

issn = "1603-9629",

publisher = "Almindelige Danske Laegeforening",

number = "5",

}

TY - JOUR

T1 - Preferences for prenatal testing among pregnant women, partners and health professionals

AU - Lund, Ida Charlotte Bay

AU - Becher, Naja

AU - Petersen, Olav Bjørn

AU - Hill, Melissa

AU - Chitty, Lyn

AU - Vogel, Ida

N1 - Articles published in the DMJ are “open access”. This means that the articles are distributed under the terms of the Creative Commons Attribution Non-commercial License, which permits any non-commercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.

PY - 2018/5

Y1 - 2018/5

N2 - INTRODUCTION: Cell-free DNA testing (cfDNA testing) in maternal plasma has recently been implemented in Danish healthcare. Prior to that we wanted to evaluate the preferences among pregnant women, partners and health professionals regarding cfDNA testing compared with invasive prenatal diagnostics. METHODS: Responders were recruited at public hospitals in the Central and North Denmark Regions. Stated preferences for prenatal testing were obtained through an online questionnaire incorporating a discrete choice experiment. Test choices differed according to attributes such as risk of miscarriage (none or small) and genetic information provided by the test; simple (Down syndrome only) or comprehensive (chromosomal abnormalities beyond Down syndrome). RESULTS: No risk of miscarriage was the key attribute affecting the preferences of women (n = 315) and partners (n = 102). However, women with experiences of invasive testing placed more emphasis on comprehensive genetic information and less on risk of miscarriage compared with other women. Likewise, foetal medicine experts, obstetricians and sonographers (n = 57) had a greater preference for comprehensive genetic information than midwives who were not directly involved in counselling for prenatal testing (n = 48). CONCLUSIONS: As safety seems to affect the majority of pregnant couples’ choice behaviour, thorough pre-test counselling by trained health professionals is of paramount importance.

AB - INTRODUCTION: Cell-free DNA testing (cfDNA testing) in maternal plasma has recently been implemented in Danish healthcare. Prior to that we wanted to evaluate the preferences among pregnant women, partners and health professionals regarding cfDNA testing compared with invasive prenatal diagnostics. METHODS: Responders were recruited at public hospitals in the Central and North Denmark Regions. Stated preferences for prenatal testing were obtained through an online questionnaire incorporating a discrete choice experiment. Test choices differed according to attributes such as risk of miscarriage (none or small) and genetic information provided by the test; simple (Down syndrome only) or comprehensive (chromosomal abnormalities beyond Down syndrome). RESULTS: No risk of miscarriage was the key attribute affecting the preferences of women (n = 315) and partners (n = 102). However, women with experiences of invasive testing placed more emphasis on comprehensive genetic information and less on risk of miscarriage compared with other women. Likewise, foetal medicine experts, obstetricians and sonographers (n = 57) had a greater preference for comprehensive genetic information than midwives who were not directly involved in counselling for prenatal testing (n = 48). CONCLUSIONS: As safety seems to affect the majority of pregnant couples’ choice behaviour, thorough pre-test counselling by trained health professionals is of paramount importance.

KW - Abortion, Spontaneous/epidemiology

KW - Adult

KW - Attitude of Health Personnel

KW - Cell-Free Nucleic Acids/analysis

KW - Choice Behavior

KW - Counseling

KW - Denmark

KW - Female

KW - Hospitals, Public

KW - Humans

KW - Male

KW - Middle Aged

KW - Patient Preference

KW - Pregnancy

KW - Prenatal Diagnosis/psychology

KW - Sexual Partners/psychology

KW - Surveys and Questionnaires

M3 - Journal article

C2 - 29726320

SN - 1603-9629

VL - 65

JO - Danish Medical Journal

JF - Danish Medical Journal

IS - 5

M1 - A5486

ER -

Preferences for prenatal testing among pregnant women, partners and health professionals

Abstract

Keywords

Access to Document

Fingerprint

Cite this