Predictors of mortality in a cohort of HIV-1-infected adults in rural Africa

TY - JOUR

T1 - Predictors of mortality in a cohort of HIV-1-infected adults in rural Africa

AU - Erikstrup, Christian

AU - Kallestrup, Per

AU - Zinyama, Rutendo

AU - Gomo, Exnevia

AU - Mudenge, Boniface

AU - Gerstoft, Jan

AU - Ullum, Henrik

PY - 2007

Y1 - 2007

N2 - CD4 cell count and plasma HIV RNA level are used to monitor HIV-infected patients in high-income countries, but the applicability in an African context with frequent concomitant infections has only been studied sparsely. Moreover, alternative inexpensive markers are needed in the attempts to roll out antiretroviral treatment in the region. We explored the prognostic strengths of classic and alternative progression markers in this study set in rural Zimbabwe.

AB - CD4 cell count and plasma HIV RNA level are used to monitor HIV-infected patients in high-income countries, but the applicability in an African context with frequent concomitant infections has only been studied sparsely. Moreover, alternative inexpensive markers are needed in the attempts to roll out antiretroviral treatment in the region. We explored the prognostic strengths of classic and alternative progression markers in this study set in rural Zimbabwe.

KW - Adult

KW - CD4 Lymphocyte Count

KW - Cohort Studies

KW - Female

KW - Follow-Up Studies

KW - HIV Infections

KW - HIV-1

KW - Hemoglobins

KW - Humans

KW - Kaplan-Meier Estimate

KW - Karnofsky Performance Status

KW - Lymphocyte Count

KW - Male

KW - Multivariate Analysis

KW - Predictive Value of Tests

KW - Prognosis

KW - Proportional Hazards Models

KW - RNA, Viral

KW - Rural Health

KW - Schistosomiasis

KW - Survival Rate

KW - Zimbabwe

U2 - 10.1097/QAI.0b013e318032bbcd

DO - 10.1097/QAI.0b013e318032bbcd

M3 - Journal article

C2 - 17259906

SN - 1525-4135

VL - 44

SP - 478

EP - 483

JO - J A I D S

JF - J A I D S

IS - 4

ER -