Post-contrast acute kidney injury. Part 2: risk stratification, role of hydration and other prophylactic measures, patients taking metformin and chronic dialysis patients: Recommendations for updated ESUR Contrast Medium Safety Committee guidelines

Aart J. van der Molen, Peter Reimer, Ilona A. Dekkers, Georg Bongartz, Marie France Bellin, Michele Bertolotto, Olivier Clement, Gertraud Heinz-Peer, Fulvio Stacul, Judith A.W. Webb, Henrik S. Thomsen*

*Corresponding author for this work
97 Citations (Scopus)
14 Downloads (Pure)

Abstract

Objectives: The Contrast Media Safety Committee (CMSC) of the European Society of Urogenital Radiology (ESUR) has updated its 2011 guidelines on the prevention of post-contrast acute kidney injury (PC-AKI). The results of the literature review and the recommendations based on it, which were used to prepare the new guidelines, are presented in two papers. Areas covered in part 2: Topics reviewed include stratification of PC-AKI risk, the need to withdraw nephrotoxic medication, PC-AKI prophylaxis with hydration or drugs, the use of metformin in diabetic patients receiving contrast medium and the need to alter dialysis schedules in patients receiving contrast medium. Key points: • In CKD, hydration reduces the PC-AKI risk • Intravenous normal saline and intravenous sodium bicarbonate provide equally effective prophylaxis • No drugs have been consistently shown to reduce the risk of PC-AKI • Stop metformin from the time of contrast medium administration if eGFR < 30 ml/min/1.73 m2 • Dialysis schedules need not change when intravascular contrast medium is given.

Original languageEnglish
JournalEuropean Radiology
Volume28
Issue number7
Pages (from-to)2856-2869
Number of pages14
ISSN0938-7994
DOIs
Publication statusPublished - 2018

Keywords

  • Acute kidney injury
  • Contrast media
  • Haemodialysis
  • Metformin
  • Practice guidelines

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