Possible autocrine loop of the epidermal growth factor system in patients with benign prostatic hyperplasia treated with finasteride: a placebo-controlled randomized study

Niels Tørring, Klaus Møller-Ernst Jensen, L Lund, J E Nielsen, Jens Christian Djurhuus, S S Poulsen, Ebba Nexø, Steen Seier Poulsen

9 Citations (Scopus)

Abstract

To analyse the expression of the epidermal growth factor (EGF) system in prostate tissue and secretions obtained from patients with benign prostatic hyperplasia (BPH) treated with or without finasteride (which primarily targets the androgen-sensitive secretory epithelial cells in the prostate, with little effect on basal epithelial and stromal cells).
Original languageEnglish
JournalB J U International (Print)
Volume89
Issue number6
Pages (from-to)583-90
Number of pages8
ISSN1464-4096
Publication statusPublished - 1 Apr 2002

Keywords

  • Epidermal Growth Factor
  • Finasteride
  • Glycoproteins
  • Growth Substances
  • Humans
  • Immunohistochemistry
  • Intercellular Signaling Peptides and Proteins
  • Male
  • Prospective Studies
  • Prostatic Hyperplasia
  • Receptor, Epidermal Growth Factor
  • Receptor, erbB-2
  • Transforming Growth Factor alpha

Fingerprint

Dive into the research topics of 'Possible autocrine loop of the epidermal growth factor system in patients with benign prostatic hyperplasia treated with finasteride: a placebo-controlled randomized study'. Together they form a unique fingerprint.

Cite this