Population pharmacokinetic estimates suggest elevated clearance and distribution volume of desethylamodiaquine in pediatric patients with sickle Cell disease treated with artesunate-amodiaquine

George O Adjei, Seth K Amponsah, Bamenla Q Goka, Christabel Enweronu-Laryea, Lorna Renner, Abdul Malik Sulley, Michael Alifrangis, Jorgen A L Kurtzhals

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Pharmacology, Toxicology and Pharmaceutical Science