Plasma TNF binding capacity in patients with juvenile idiopathic arthritis

TY - JOUR

T1 - Plasma TNF binding capacity in patients with juvenile idiopathic arthritis

AU - Bjørnhart, Birgitte

AU - Svenningsen, Pernille

AU - Gudbrandsdottir, Sif

AU - Zak, Marek

AU - Nielsen, Susan

AU - Bendtzen, Klaus

AU - Müller, Klaus

PY - 2005/1/1

Y1 - 2005/1/1

N2 - Tumour necrosis factor (TNF)-alpha and TNF-beta, also called lymphotoxin (LT), are bound by soluble truncated TNF receptors (sTNFRI and II) that are released from cell surfaces and act as natural inhibitors of TNF-induced inflammation. We investigated the plasma levels of sTNFRI and II in parallel with LT binding capacity (LTBC) in 44 patients with juvenile chronic arthritis (JIA).

AB - Tumour necrosis factor (TNF)-alpha and TNF-beta, also called lymphotoxin (LT), are bound by soluble truncated TNF receptors (sTNFRI and II) that are released from cell surfaces and act as natural inhibitors of TNF-induced inflammation. We investigated the plasma levels of sTNFRI and II in parallel with LT binding capacity (LTBC) in 44 patients with juvenile chronic arthritis (JIA).

KW - Adolescent

KW - Arthritis, Juvenile Rheumatoid

KW - Child

KW - Child, Preschool

KW - Enzyme-Linked Immunosorbent Assay

KW - Female

KW - Humans

KW - Infant

KW - Lymphotoxin-alpha

KW - Male

KW - Receptors, Tumor Necrosis Factor, Type I

KW - Receptors, Tumor Necrosis Factor, Type II

KW - Recombinant Proteins

U2 - 10.1016/j.intimp.2004.09.022

DO - 10.1016/j.intimp.2004.09.022

M3 - Journal article

C2 - 15589462

SN - 1567-5769

VL - 5

SP - 73

EP - 77

JO - International Immunopharmacology

JF - International Immunopharmacology

IS - 1

ER -