Abstract
The current state, tools, and applications of personalized medicine with special emphasis on inflammatory skin diseases like psoriasis and atopic dermatitis are discussed. Inflammatory pathways are outlined as well as potential targets for monoclonal antibodies and small-molecule inhibitors
Original language | English |
---|---|
Journal | APMIS - Journal of Pathology, Microbiology and Immunology |
Volume | 127 |
Issue number | 5 |
Pages (from-to) | 386-424 |
Number of pages | 39 |
ISSN | 0903-4641 |
DOIs | |
Publication status | Published - May 2019 |
Keywords
- Bioinformatics
- Biomarkers
- Dermatitis,Atopic
- drug therapy
- review article
- genetics
- Epigenomics
- personalized medicine
- endotypes
- Precision Medicine
- methods
- inflammatory disorders
- Psoriasis
- Transcriptomics
- Whole Genome Sequencing
- targeted therapy