Permeability and ultrastructure of human bladder epithelium

J Eldrup, Jørgen Mogens Thorup, S L Nielsen, T Hald, B Hainau

    59 Citations (Scopus)

    Abstract

    Leakage of tight junctions as observed with electron microscopy and demonstration of solute transport across bladder epithelium was investigated in 13 patients with different bladder diseases: urinary retention and infection, bladder tumours and interstitial cystitis. The latter group showed consistent leakage of solutes through the urothelium. Electron microscopy revealed leaky tight junctions. This finding might be helpful in establishing the histological criteria and explain the pathogenesis of interstitial cystitis.
    Original languageEnglish
    JournalBritish Journal of Urology
    Volume55
    Issue number5
    Pages (from-to)488-92
    Number of pages5
    ISSN0007-1331
    Publication statusPublished - Oct 1983

    Keywords

    • Adult
    • Albumins
    • Cell Membrane Permeability
    • Epithelium
    • Female
    • Humans
    • Intercellular Junctions
    • Male
    • Microscopy, Electron
    • Middle Aged
    • Sodium
    • Urea
    • Urinary Bladder
    • Urologic Diseases

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