Abstract
Background: Transfusion with red blood cells (RBC) may be needed during hip revision surgery but the appropriate haemoglobin concentration (Hb) threshold for transfusion has not been well established. We hypothesized that a higher transfusion threshold would improve ambulation after hip revision surgery. Methods: going hip revision surgery were randomized to receive RBC at a Hb threshold of either 7.3 g/dL (restrictive group) or 8.9 g/dL (liberal group). Postoperative ambulation was assessed using Timed Up and Go-test (TUG) and ability to walk was also assessed daily by a physiotherapist blinded to the allocation. Results: Fifty-three patients were able to perform the TUG and included in the analysis. The TUG could be completed in a median of 36 sec vs. 30 sec in the restrictive group and the liberal group, respectively (P = 0.02). The mean difference in TUG was 14.5 sec (95%CI 2.8-26.2 sec). No difference was found in the day patients could perform TUG or walk 10 meters. The Hb at the day of testing was 10.2 g/dL in the restrictive group and 9.9 g/dL in the liberal group. Only 26 patients received RBC. Conclusions: A Hb transfusion threshold of 8.9 g/dL was associated with a statistically significantly faster TUG after hip revision surgery compared to a threshold of 7.3 g/dL but the clinical importance is questionable and the groups did not differ in Hb at the time of testing.
| Original language | English |
|---|---|
| Journal | B M C Anesthesiology |
| Volume | 14 |
| Pages (from-to) | 1-9 |
| Number of pages | 9 |
| ISSN | 1471-2253 |
| DOIs | |
| Publication status | Published - 2014 |
Keywords
- Adult
- Aged
- Aged, 80 and over
- Blood Transfusion
- Early Ambulation
- Female
- Fluid Therapy
- Hemoglobins
- Hip
- Humans
- Male
- Middle Aged
- Orthopedic Procedures
- Pain Management
- Pain, Postoperative
- Perioperative Period