Peptide Half-Life Extension: Divalent, Small-Molecule Albumin Interactions Direct the Systemic Properties of Glucagon-Like Peptide 1 (GLP-1) Analogues

Esben M. Bech; Manuel C. Martos-Maldonado; Pernille Wismann; Kasper K. Sorensen; Soren Blok van Witteloostuijn; Mikkel B. Thygesen; Niels Vrang; Jacob Jelsing; Soren L. Pedersen; Knud J. Jensen

doi:10.1021/acs.jmedchem.7b00787

Peptide Half-Life Extension: Divalent, Small-Molecule Albumin Interactions Direct the Systemic Properties of Glucagon-Like Peptide 1 (GLP-1) Analogues

Esben M. Bech, Manuel C. Martos-Maldonado, Pernille Wismann, Kasper K. Sorensen, Soren Blok van Witteloostuijn, Mikkel B. Thygesen, Niels Vrang, Jacob Jelsing, Soren L. Pedersen, Knud J. Jensen

Department of Chemistry

19 Citations (Scopus)

Original language	English
Journal	Journal of Medicinal Chemistry
Volume	60
Issue number	17
Pages (from-to)	7434-7446
Number of pages	13
ISSN	0022-2623
DOIs	https://doi.org/10.1021/acs.jmedchem.7b00787
Publication status	Published - 14 Sept 2017

Access to Document

10.1021/acs.jmedchem.7b00787

Cite this

Bech, E. M., Martos-Maldonado, M. C., Wismann, P., Sorensen, K. K., van Witteloostuijn, S. B., Thygesen, M. B., Vrang, N., Jelsing, J., Pedersen, S. L., & Jensen, K. J. (2017). Peptide Half-Life Extension: Divalent, Small-Molecule Albumin Interactions Direct the Systemic Properties of Glucagon-Like Peptide 1 (GLP-1) Analogues. Journal of Medicinal Chemistry, 60(17), 7434-7446. https://doi.org/10.1021/acs.jmedchem.7b00787

Peptide Half-Life Extension : Divalent, Small-Molecule Albumin Interactions Direct the Systemic Properties of Glucagon-Like Peptide 1 (GLP-1) Analogues. / Bech, Esben M.; Martos-Maldonado, Manuel C.; Wismann, Pernille et al.

In: Journal of Medicinal Chemistry, Vol. 60, No. 17, 14.09.2017, p. 7434-7446.

Research output: Contribution to journal › Journal article › Research › peer-review

Bech, EM, Martos-Maldonado, MC, Wismann, P, Sorensen, KK, van Witteloostuijn, SB, Thygesen, MB, Vrang, N, Jelsing, J, Pedersen, SL & Jensen, KJ 2017, 'Peptide Half-Life Extension: Divalent, Small-Molecule Albumin Interactions Direct the Systemic Properties of Glucagon-Like Peptide 1 (GLP-1) Analogues', Journal of Medicinal Chemistry, vol. 60, no. 17, pp. 7434-7446. https://doi.org/10.1021/acs.jmedchem.7b00787

@article{30e869990de1423db06984c4e6446a45,

title = "Peptide Half-Life Extension: Divalent, Small-Molecule Albumin Interactions Direct the Systemic Properties of Glucagon-Like Peptide 1 (GLP-1) Analogues",

author = "Bech, {Esben M.} and Martos-Maldonado, {Manuel C.} and Pernille Wismann and Sorensen, {Kasper K.} and {van Witteloostuijn}, {Soren Blok} and Thygesen, {Mikkel B.} and Niels Vrang and Jacob Jelsing and Pedersen, {Soren L.} and Jensen, {Knud J.}",

year = "2017",

month = sep,

day = "14",

doi = "10.1021/acs.jmedchem.7b00787",

language = "English",

volume = "60",

pages = "7434--7446",

journal = "Journal of Medicinal Chemistry",

issn = "0022-2623",

publisher = "American Chemical Society",

number = "17",

}

TY - JOUR

T1 - Peptide Half-Life Extension

T2 - Divalent, Small-Molecule Albumin Interactions Direct the Systemic Properties of Glucagon-Like Peptide 1 (GLP-1) Analogues

AU - Bech, Esben M.

AU - Martos-Maldonado, Manuel C.

AU - Wismann, Pernille

AU - Sorensen, Kasper K.

AU - van Witteloostuijn, Soren Blok

AU - Thygesen, Mikkel B.

AU - Vrang, Niels

AU - Jelsing, Jacob

AU - Pedersen, Soren L.

AU - Jensen, Knud J.

PY - 2017/9/14

Y1 - 2017/9/14

U2 - 10.1021/acs.jmedchem.7b00787

DO - 10.1021/acs.jmedchem.7b00787

M3 - Journal article

C2 - 28771355

SN - 0022-2623

VL - 60

SP - 7434

EP - 7446

JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

IS - 17

ER -

Peptide Half-Life Extension: Divalent, Small-Molecule Albumin Interactions Direct the Systemic Properties of Glucagon-Like Peptide 1 (GLP-1) Analogues

Access to Document

Fingerprint

Cite this