Penile vibratory stimulation in the treatment of post-prostatectomy incontinence: A randomized pilot study

TY - JOUR

T1 - Penile vibratory stimulation in the treatment of post-prostatectomy incontinence

T2 - A randomized pilot study

AU - Fode, Mikkel

AU - Sønksen, Jens

N1 - © 2013 Wiley Periodicals, Inc.

PY - 2015/2/1

Y1 - 2015/2/1

N2 - Aims To examine penile vibratory stimulation (PVS) in the treatment of post-prostatectomy urinary incontinence (UI). Methods Patients with post-prostatectomy UI were included in a 12-week trial. A 24-hr pad test and a 72-hr voiding diary were collected at baseline. Participants were randomized to receive PVS for the first 6 weeks (group 1) or for the final 6 weeks (group 2) of the study. The primary outcome was the difference in leakage between groups 1 and 2 at 6 weeks as measured by changes in the pad test. The trial was registered at www.clinicaltrials.org (NCT01540656). Results Data from 31 men were available for analyses. The difference in the change on the pad test between the groups did not reach statistical significance at 6 weeks (P = 0.13) while the change in incontinence episodes between groups approached statistical significance (P = 0.052). However, there was a median reduction of -33 g (P = 0.021) on the pad test and a median reduction in daily incontinence episodes of -1 (P = 0.023) in group 1 at 6 weeks. At 12 weeks, group 2 had a median decrease on the pad test of -8 g (P = 0.10) and no change in incontinence episodes. A pooled analysis showed a decline on the pad test of -13.5 g (P = 0.004) after PVS. Small improvements were seen in subjective symptom scores and 58% stated to be satisfied with PVS. Self-limiting side effects were experienced by 15% of patients. Conclusions PVS is feasible in the treatment of post-prostatectomy UI. Larger trials are needed to document the clinical efficacy. Neurourol. Urodynam. 34:117-122, 2015.

AB - Aims To examine penile vibratory stimulation (PVS) in the treatment of post-prostatectomy urinary incontinence (UI). Methods Patients with post-prostatectomy UI were included in a 12-week trial. A 24-hr pad test and a 72-hr voiding diary were collected at baseline. Participants were randomized to receive PVS for the first 6 weeks (group 1) or for the final 6 weeks (group 2) of the study. The primary outcome was the difference in leakage between groups 1 and 2 at 6 weeks as measured by changes in the pad test. The trial was registered at www.clinicaltrials.org (NCT01540656). Results Data from 31 men were available for analyses. The difference in the change on the pad test between the groups did not reach statistical significance at 6 weeks (P = 0.13) while the change in incontinence episodes between groups approached statistical significance (P = 0.052). However, there was a median reduction of -33 g (P = 0.021) on the pad test and a median reduction in daily incontinence episodes of -1 (P = 0.023) in group 1 at 6 weeks. At 12 weeks, group 2 had a median decrease on the pad test of -8 g (P = 0.10) and no change in incontinence episodes. A pooled analysis showed a decline on the pad test of -13.5 g (P = 0.004) after PVS. Small improvements were seen in subjective symptom scores and 58% stated to be satisfied with PVS. Self-limiting side effects were experienced by 15% of patients. Conclusions PVS is feasible in the treatment of post-prostatectomy UI. Larger trials are needed to document the clinical efficacy. Neurourol. Urodynam. 34:117-122, 2015.

KW - Aged

KW - Feasibility Studies

KW - Follow-Up Studies

KW - Humans

KW - Incidence

KW - Incontinence Pads

KW - Male

KW - Middle Aged

KW - Penis

KW - Physical Stimulation

KW - Pilot Projects

KW - Prostatectomy

KW - Self Report

KW - Treatment Outcome

KW - Urinary Incontinence

KW - Vibration

U2 - 10.1002/nau.22536

DO - 10.1002/nau.22536

M3 - Journal article

C2 - 24285576

SN - 0733-2467

VL - 34

SP - 117

EP - 122

JO - Neurourology and Urodynamics

JF - Neurourology and Urodynamics

IS - 2

ER -