Patients Diagnosed With Severe Adult GH Deficiency Using The Insulin Tolerance Test, Arginine Or Glucagon Stimulation Tests Share Similar Clinical Features

Andy Toogood, Georg Brabant, Dominique Maiter, Björn Jonsson, Ulla Feldt-Rasmussen, Maria Koltowska-Haggstrom, Åse Krogh Rasmussen, Michael Buchfelder, Bernhard Saller, Beverly M K Biller

    13 Citations (Scopus)

    Abstract

    Objective: To determine whether the ITT, arginine (AST) and glucagon stimulation tests (GST) identify patients who have similar features of GH deficiency using a diagnostic threshold of 3 µg/l.Patients and Methods: 5453 tests were available from 4,867 patients registered in the KIMS database (49.9% females, ITT = 3111, AST = 1390, GST = 952). Comparisons were made for GH peak, BMI, lipids, waist circumference, waist:hip ratio and quality of life (QoL-AGHDA questionnaire).Results. There were significant (p
    Original languageEnglish
    JournalEndocrine Practice
    Pages (from-to)1-26
    Number of pages27
    ISSN1530-891X
    DOIs
    Publication statusPublished - 2011

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