Parasympathetic neural activity accounts for the lowering of exercise heart rate at high altitude

Robert Christopher Boushel, J A Calbet, G Rådegran, H Sondergaard, Poul Erik Wagner, B Saltin

112 Citations (Scopus)

Abstract

In chronic hypoxia, both heart rate (HR) and cardiac output (Q) are reduced during exercise. The role of parasympathetic neural activity in lowering HR is unresolved, and its influence on Q and oxygen transport at high altitude has never been studied.
Original languageEnglish
JournalCirculation
Volume104
Issue number15
Pages (from-to)1785-91
Number of pages7
ISSN0009-7322
Publication statusPublished - 9 Oct 2001

Keywords

  • Acclimatization
  • Adult
  • Altitude
  • Anoxia
  • Blood Flow Velocity
  • Blood Pressure
  • Cardiac Output
  • Chronic Disease
  • Exercise
  • Exercise Test
  • Female
  • Glycopyrrolate
  • Heart Rate
  • Humans
  • Leg
  • Male
  • Oxygen Consumption
  • Parasympathetic Nervous System
  • Reference Values
  • Regional Blood Flow
  • Vagus Nerve

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