Pannexin-2-deficiency sensitizes pancreatic beta-cells to cytokine-induced apoptosis in vitro and impairs glucose tolerance in vivo

Lukas A. Berchtold; Michela Miani; Thi A. Diep; Andreas N. Madsen; Valentina Cigliola; Maikel Colli; Jelena M. Krivokapic; Flemming Pociot; Decio L. Eizirik; Paolo Meda; Birgitte Hoist; Nils Billestrup; Joachim Storling

doi:10.1016/j.mce.2017.04.001

Pannexin-2-deficiency sensitizes pancreatic beta-cells to cytokine-induced apoptosis in vitro and impairs glucose tolerance in vivo

Lukas A. Berchtold, Michela Miani, Thi A. Diep, Andreas N. Madsen, Valentina Cigliola, Maikel Colli, Jelena M. Krivokapic, Flemming Pociot, Decio L. Eizirik, Paolo Meda, Birgitte Hoist, Nils Billestrup, Joachim Storling

5 Citations (Scopus)

Original language	English
Journal	Molecular and Cellular Endocrinology
Volume	448
Pages (from-to)	108-121
Number of pages	4
ISSN	0303-7207
DOIs	https://doi.org/10.1016/j.mce.2017.04.001
Publication status	Published - 15 Jun 2017

Keywords

Apoptosis
beta-cell
Cytokine
Insulin
Type 1 diabetes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Berchtold, L. A., Miani, M., Diep, T. A., Madsen, A. N., Cigliola, V., Colli, M., Krivokapic, J. M., Pociot, F., Eizirik, D. L., Meda, P., Hoist, B., Billestrup, N., & Storling, J. (2017). Pannexin-2-deficiency sensitizes pancreatic beta-cells to cytokine-induced apoptosis in vitro and impairs glucose tolerance in vivo. Molecular and Cellular Endocrinology, 448, 108-121. https://doi.org/10.1016/j.mce.2017.04.001

Berchtold, LA, Miani, M, Diep, TA, Madsen, AN, Cigliola, V, Colli, M, Krivokapic, JM, Pociot, F, Eizirik, DL, Meda, P, Hoist, B , Billestrup, N & Storling, J 2017, 'Pannexin-2-deficiency sensitizes pancreatic beta-cells to cytokine-induced apoptosis in vitro and impairs glucose tolerance in vivo', Molecular and Cellular Endocrinology, vol. 448, pp. 108-121. https://doi.org/10.1016/j.mce.2017.04.001

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title = "Pannexin-2-deficiency sensitizes pancreatic beta-cells to cytokine-induced apoptosis in vitro and impairs glucose tolerance in vivo",

keywords = "Apoptosis, beta-cell, Cytokine, Insulin, Type 1 diabetes",

author = "Berchtold, {Lukas A.} and Michela Miani and Diep, {Thi A.} and Madsen, {Andreas N.} and Valentina Cigliola and Maikel Colli and Krivokapic, {Jelena M.} and Flemming Pociot and Eizirik, {Decio L.} and Paolo Meda and Birgitte Hoist and Nils Billestrup and Joachim Storling",

year = "2017",

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day = "15",

doi = "10.1016/j.mce.2017.04.001",

language = "English",

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journal = "Molecular and Cellular Endocrinology",

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TY - JOUR

T1 - Pannexin-2-deficiency sensitizes pancreatic beta-cells to cytokine-induced apoptosis in vitro and impairs glucose tolerance in vivo

AU - Berchtold, Lukas A.

AU - Miani, Michela

AU - Diep, Thi A.

AU - Madsen, Andreas N.

AU - Cigliola, Valentina

AU - Colli, Maikel

AU - Krivokapic, Jelena M.

AU - Pociot, Flemming

AU - Eizirik, Decio L.

AU - Meda, Paolo

AU - Hoist, Birgitte

AU - Billestrup, Nils

AU - Storling, Joachim

PY - 2017/6/15

Y1 - 2017/6/15

KW - Apoptosis

KW - beta-cell

KW - Cytokine

KW - Insulin

KW - Type 1 diabetes

U2 - 10.1016/j.mce.2017.04.001

DO - 10.1016/j.mce.2017.04.001

M3 - Journal article

C2 - 28390953

SN - 0303-7207

VL - 448

SP - 108

EP - 121

JO - Molecular and Cellular Endocrinology

JF - Molecular and Cellular Endocrinology

ER -

Pannexin-2-deficiency sensitizes pancreatic beta-cells to cytokine-induced apoptosis in vitro and impairs glucose tolerance in vivo

Keywords

UN SDGs

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