Outbreak of Clostridium difficile 027 in North Zealand, Denmark, 2008-2009

S Bacci; G St-Martin; B Olesen; B Bruun; K E P Olsen; E Møller Nielsen; K Mølbak

Outbreak of Clostridium difficile 027 in North Zealand, Denmark, 2008-2009

S Bacci, G St-Martin, B Olesen, B Bruun, K E P Olsen, E Møller Nielsen, K Mølbak

Section 05 - Community Dentistry

26 Citations (Scopus)

Abstract

We report an outbreak of Clostridium difficile PCR ribotype 027 in Denmark. The outbreak includes to date 73 cases from the area north of Copenhagen, but there may be related cases elsewhere in Zealand. Most infections are healthcare-associated and in patients who previously received antibiotic treatment. The strain is resistant to moxifloxacin, erythromycin, and clindamycin, and carries genes for toxin A, toxin B, and for the binary toxin. The antimicrobial pattern differs from that of the strain involved in a small cluster in Denmark in 2006-2007. Because of this outbreak, hygienic measures in the involved hospitals have been reinforced. Nationwide, microbiological laboratories were alerted to the outbreak and encouraged to send isolates for toxin profiling and PCR ribotyping.

Original language	English
Journal	Eurosurveillance (Print Edition)
Volume	14
Issue number	16
Pages (from-to)	19183
ISSN	1025-496X
Publication status	Published - 2009

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title = "Outbreak of Clostridium difficile 027 in North Zealand, Denmark, 2008-2009",

abstract = "We report an outbreak of Clostridium difficile PCR ribotype 027 in Denmark. The outbreak includes to date 73 cases from the area north of Copenhagen, but there may be related cases elsewhere in Zealand. Most infections are healthcare-associated and in patients who previously received antibiotic treatment. The strain is resistant to moxifloxacin, erythromycin, and clindamycin, and carries genes for toxin A, toxin B, and for the binary toxin. The antimicrobial pattern differs from that of the strain involved in a small cluster in Denmark in 2006-2007. Because of this outbreak, hygienic measures in the involved hospitals have been reinforced. Nationwide, microbiological laboratories were alerted to the outbreak and encouraged to send isolates for toxin profiling and PCR ribotyping.",

author = "S Bacci and G St-Martin and B Olesen and B Bruun and Olsen, {K E P} and Nielsen, {E M{\o}ller} and K M{\o}lbak",

note = "Keywords: Aged; Aged, 80 and over; Base Sequence; Clostridium difficile; Denmark; Disease Outbreaks; Enterocolitis, Pseudomembranous; Humans; Ribotyping",

year = "2009",

language = "English",

volume = "14",

pages = "19183",

journal = "Eurosurveillance (Print Edition)",

issn = "1025-496X",

publisher = "Centre Europeen pour la Surveillance Epidemiologique du SIDA",

number = "16",

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TY - JOUR

T1 - Outbreak of Clostridium difficile 027 in North Zealand, Denmark, 2008-2009

AU - Bacci, S

AU - St-Martin, G

AU - Olesen, B

AU - Bruun, B

AU - Olsen, K E P

AU - Nielsen, E Møller

AU - Mølbak, K

N1 - Keywords: Aged; Aged, 80 and over; Base Sequence; Clostridium difficile; Denmark; Disease Outbreaks; Enterocolitis, Pseudomembranous; Humans; Ribotyping

PY - 2009

Y1 - 2009

N2 - We report an outbreak of Clostridium difficile PCR ribotype 027 in Denmark. The outbreak includes to date 73 cases from the area north of Copenhagen, but there may be related cases elsewhere in Zealand. Most infections are healthcare-associated and in patients who previously received antibiotic treatment. The strain is resistant to moxifloxacin, erythromycin, and clindamycin, and carries genes for toxin A, toxin B, and for the binary toxin. The antimicrobial pattern differs from that of the strain involved in a small cluster in Denmark in 2006-2007. Because of this outbreak, hygienic measures in the involved hospitals have been reinforced. Nationwide, microbiological laboratories were alerted to the outbreak and encouraged to send isolates for toxin profiling and PCR ribotyping.

AB - We report an outbreak of Clostridium difficile PCR ribotype 027 in Denmark. The outbreak includes to date 73 cases from the area north of Copenhagen, but there may be related cases elsewhere in Zealand. Most infections are healthcare-associated and in patients who previously received antibiotic treatment. The strain is resistant to moxifloxacin, erythromycin, and clindamycin, and carries genes for toxin A, toxin B, and for the binary toxin. The antimicrobial pattern differs from that of the strain involved in a small cluster in Denmark in 2006-2007. Because of this outbreak, hygienic measures in the involved hospitals have been reinforced. Nationwide, microbiological laboratories were alerted to the outbreak and encouraged to send isolates for toxin profiling and PCR ribotyping.

M3 - Journal article

C2 - 19389341

SN - 1025-496X

VL - 14

SP - 19183

JO - Eurosurveillance (Print Edition)

JF - Eurosurveillance (Print Edition)

IS - 16

ER -

Outbreak of Clostridium difficile 027 in North Zealand, Denmark, 2008-2009

Abstract

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