Out-of-hospital cardiac arrests in children and adolescents: incidences, outcomes, and household socioeconomic status

Shahzleen Rajan; Mads Wissenberg; Fredrik Folke; Carolina Malta Hansen; Freddy K Lippert; Peter Weeke; Lena Karlsson; Kathrine Bach Søndergaard; Kristian Kragholm; Erika Frischknecht Christensen; Søren L Nielsen; Lars Kober; Gunnar H Gislason; Christian Torp-Pedersen

doi:10.1016/j.resuscitation.2014.11.025

Out-of-hospital cardiac arrests in children and adolescents: incidences, outcomes, and household socioeconomic status

Shahzleen Rajan, Mads Wissenberg, Fredrik Folke, Carolina Malta Hansen, Freddy K Lippert, Peter Weeke, Lena Karlsson, Kathrine Bach Søndergaard, Kristian Kragholm, Erika Frischknecht Christensen, Søren L Nielsen, Lars Kober, Gunnar H Gislason, Christian Torp-Pedersen

Department of Clinical Medicine

39 Citations (Scopus)

Abstract

Background: There is insufficient knowledge of out-of-hospital cardiac arrest (OHCA) in the very young. Objectives: This nationwide study sought to examine age-stratified OHCA characteristics and the role of parental socioeconomic differences and its contribution to mortality in the young population. Methods: All OHCA patients in Denmark, ≤21 years of age, were identified from 2001 to 2010. The population was divided into infants (<1 year); pre-school children (1-5 years); school children (6-15 years); and high school adolescents/young adults (16-21 years). Multivariate logistic regression analyses were used to investigate associations between pre-hospital factors and study endpoints: return of spontaneous circulation and survival. Results: A total of 459 individuals were included. Overall incidence of OHCA was 3.3 per 100,000 inhabitants per year. The incidence rates for infants, pre-school children, school children and high school adolescents were 11.5, 3.5, 1.3 and 5.3 per 100,000 inhabitants. Overall bystander CPR rate was 48.8%, and for age groups: 55.4%, 41.2%, 44.9% and 63.0%, respectively. Overall 30-day survival rate was 8.1%, and for age groups: 1.4%, 4.5%, 16.1% and 9.3%, respectively. High parental education was associated with improved survival after OHCA (OR 3.48, CI 1.27-9.41). Significant crude difference in survival (OR 3.18, CI 1.22-8.34) between high household incomes vs. low household incomes was found. Conclusion: OHCA incidences and survival rates varied significantly between age groups. High parental education was found to be associated with improved survival after OHCA.

Original language	English
Journal	Resuscitation
Volume	88
Pages (from-to)	12-9
Number of pages	8
ISSN	0300-9572
DOIs	https://doi.org/10.1016/j.resuscitation.2014.11.025
Publication status	Published - 1 Mar 2015

Keywords

Adolescent
Cardiopulmonary Resuscitation
Child
Child, Preschool
Denmark
Emergency Medical Services
Female
Humans
Incidence
Infant
Male
Out-of-Hospital Cardiac Arrest
Registries
Socioeconomic Factors
Survival Rate
Time Factors
Young Adult

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10.1016/j.resuscitation.2014.11.025

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Rajan, S., Wissenberg, M., Folke, F., Hansen, C. M., Lippert, F. K., Weeke, P., Karlsson, L., Søndergaard, K. B., Kragholm, K., Christensen, E. F., Nielsen, S. L., Kober, L., Gislason, G. H., & Torp-Pedersen, C. (2015). Out-of-hospital cardiac arrests in children and adolescents: incidences, outcomes, and household socioeconomic status. Resuscitation, 88, 12-9. https://doi.org/10.1016/j.resuscitation.2014.11.025

Rajan, S, Wissenberg, M, Folke, F, Hansen, CM, Lippert, FK, Weeke, P, Karlsson, L, Søndergaard, KB, Kragholm, K, Christensen, EF, Nielsen, SL, Kober, L , Gislason, GH & Torp-Pedersen, C 2015, 'Out-of-hospital cardiac arrests in children and adolescents: incidences, outcomes, and household socioeconomic status', Resuscitation, vol. 88, pp. 12-9. https://doi.org/10.1016/j.resuscitation.2014.11.025

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title = "Out-of-hospital cardiac arrests in children and adolescents: incidences, outcomes, and household socioeconomic status",

abstract = "Background: There is insufficient knowledge of out-of-hospital cardiac arrest (OHCA) in the very young. Objectives: This nationwide study sought to examine age-stratified OHCA characteristics and the role of parental socioeconomic differences and its contribution to mortality in the young population. Methods: All OHCA patients in Denmark, ≤21 years of age, were identified from 2001 to 2010. The population was divided into infants (<1 year); pre-school children (1-5 years); school children (6-15 years); and high school adolescents/young adults (16-21 years). Multivariate logistic regression analyses were used to investigate associations between pre-hospital factors and study endpoints: return of spontaneous circulation and survival. Results: A total of 459 individuals were included. Overall incidence of OHCA was 3.3 per 100,000 inhabitants per year. The incidence rates for infants, pre-school children, school children and high school adolescents were 11.5, 3.5, 1.3 and 5.3 per 100,000 inhabitants. Overall bystander CPR rate was 48.8%, and for age groups: 55.4%, 41.2%, 44.9% and 63.0%, respectively. Overall 30-day survival rate was 8.1%, and for age groups: 1.4%, 4.5%, 16.1% and 9.3%, respectively. High parental education was associated with improved survival after OHCA (OR 3.48, CI 1.27-9.41). Significant crude difference in survival (OR 3.18, CI 1.22-8.34) between high household incomes vs. low household incomes was found. Conclusion: OHCA incidences and survival rates varied significantly between age groups. High parental education was found to be associated with improved survival after OHCA.",

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author = "Shahzleen Rajan and Mads Wissenberg and Fredrik Folke and Hansen, {Carolina Malta} and Lippert, {Freddy K} and Peter Weeke and Lena Karlsson and S{\o}ndergaard, {Kathrine Bach} and Kristian Kragholm and Christensen, {Erika Frischknecht} and Nielsen, {S{\o}ren L} and Lars Kober and Gislason, {Gunnar H} and Christian Torp-Pedersen",

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doi = "10.1016/j.resuscitation.2014.11.025",

language = "English",

volume = "88",

pages = "12--9",

journal = "Resuscitation",

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TY - JOUR

T1 - Out-of-hospital cardiac arrests in children and adolescents

T2 - incidences, outcomes, and household socioeconomic status

AU - Rajan, Shahzleen

AU - Wissenberg, Mads

AU - Folke, Fredrik

AU - Hansen, Carolina Malta

AU - Lippert, Freddy K

AU - Weeke, Peter

AU - Karlsson, Lena

AU - Søndergaard, Kathrine Bach

AU - Kragholm, Kristian

AU - Christensen, Erika Frischknecht

AU - Nielsen, Søren L

AU - Kober, Lars

AU - Gislason, Gunnar H

AU - Torp-Pedersen, Christian

PY - 2015/3/1

Y1 - 2015/3/1

N2 - Background: There is insufficient knowledge of out-of-hospital cardiac arrest (OHCA) in the very young. Objectives: This nationwide study sought to examine age-stratified OHCA characteristics and the role of parental socioeconomic differences and its contribution to mortality in the young population. Methods: All OHCA patients in Denmark, ≤21 years of age, were identified from 2001 to 2010. The population was divided into infants (<1 year); pre-school children (1-5 years); school children (6-15 years); and high school adolescents/young adults (16-21 years). Multivariate logistic regression analyses were used to investigate associations between pre-hospital factors and study endpoints: return of spontaneous circulation and survival. Results: A total of 459 individuals were included. Overall incidence of OHCA was 3.3 per 100,000 inhabitants per year. The incidence rates for infants, pre-school children, school children and high school adolescents were 11.5, 3.5, 1.3 and 5.3 per 100,000 inhabitants. Overall bystander CPR rate was 48.8%, and for age groups: 55.4%, 41.2%, 44.9% and 63.0%, respectively. Overall 30-day survival rate was 8.1%, and for age groups: 1.4%, 4.5%, 16.1% and 9.3%, respectively. High parental education was associated with improved survival after OHCA (OR 3.48, CI 1.27-9.41). Significant crude difference in survival (OR 3.18, CI 1.22-8.34) between high household incomes vs. low household incomes was found. Conclusion: OHCA incidences and survival rates varied significantly between age groups. High parental education was found to be associated with improved survival after OHCA.

AB - Background: There is insufficient knowledge of out-of-hospital cardiac arrest (OHCA) in the very young. Objectives: This nationwide study sought to examine age-stratified OHCA characteristics and the role of parental socioeconomic differences and its contribution to mortality in the young population. Methods: All OHCA patients in Denmark, ≤21 years of age, were identified from 2001 to 2010. The population was divided into infants (<1 year); pre-school children (1-5 years); school children (6-15 years); and high school adolescents/young adults (16-21 years). Multivariate logistic regression analyses were used to investigate associations between pre-hospital factors and study endpoints: return of spontaneous circulation and survival. Results: A total of 459 individuals were included. Overall incidence of OHCA was 3.3 per 100,000 inhabitants per year. The incidence rates for infants, pre-school children, school children and high school adolescents were 11.5, 3.5, 1.3 and 5.3 per 100,000 inhabitants. Overall bystander CPR rate was 48.8%, and for age groups: 55.4%, 41.2%, 44.9% and 63.0%, respectively. Overall 30-day survival rate was 8.1%, and for age groups: 1.4%, 4.5%, 16.1% and 9.3%, respectively. High parental education was associated with improved survival after OHCA (OR 3.48, CI 1.27-9.41). Significant crude difference in survival (OR 3.18, CI 1.22-8.34) between high household incomes vs. low household incomes was found. Conclusion: OHCA incidences and survival rates varied significantly between age groups. High parental education was found to be associated with improved survival after OHCA.

KW - Adolescent

KW - Cardiopulmonary Resuscitation

KW - Child

KW - Child, Preschool

KW - Denmark

KW - Emergency Medical Services

KW - Female

KW - Humans

KW - Incidence

KW - Infant

KW - Male

KW - Out-of-Hospital Cardiac Arrest

KW - Registries

KW - Socioeconomic Factors

KW - Survival Rate

KW - Time Factors

KW - Young Adult

U2 - 10.1016/j.resuscitation.2014.11.025

DO - 10.1016/j.resuscitation.2014.11.025

M3 - Journal article

C2 - 25500748

SN - 0300-9572

VL - 88

SP - 12

EP - 19

JO - Resuscitation

JF - Resuscitation

ER -

Out-of-hospital cardiac arrests in children and adolescents: incidences, outcomes, and household socioeconomic status

Abstract

Keywords

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