Opsætning af screeningsprogram i Danmark for føtal og neonatal alloimmun trombocytopeni

Caroline Madsen; Kira Philipsen Prahm; Cecilia Nilsson; Lars Henning Pedersen; Morten Hanefeld Dziegiel; Morten Hedegaard

Opsætning af screeningsprogram i Danmark for føtal og neonatal alloimmun trombocytopeni

Translated title of the contribution: Establishing a screening programme in Denmark for foetal and neonatal alloimmune thrombocytopenia

Caroline Madsen, Kira Philipsen Prahm, Cecilia Nilsson, Lars Henning Pedersen, Morten Hanefeld Dziegiel, Morten Hedegaard

Department of Clinical Medicine

1 Citation (Scopus)

Abstract

Foetal and neonatal alloimmune thrombocytopenia (FNAIT) can cause cerebral haemorrhage in newborns. FNAIT occurs in women, who do not have the thrombocyte type human platelet antigen (HPA)-1a and are carrying an HPA-1a positive foetus. Maternal antibodies can cause thrombocytopenia in the foetus or newborn. Antenatal screening for FNAIT can easily be integrated in the already existing national screening programme for rhesus immunisation. Prophylactic treatment with immunoglobulines for pregnancies at risk can prevent neonatal complications. We argue, that the WHO criteria for a screening programme for FNAIT are met.

Translated title of the contribution	Establishing a screening programme in Denmark for foetal and neonatal alloimmune thrombocytopenia
Original language	Danish
Article number	V03170211
Journal	Ugeskrift for Laeger
Volume	180
Issue number	17
Pages (from-to)	2-6
Number of pages	5
ISSN	0041-5782
Publication status	Published - 2018

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http://ugeskriftet.dk/videnskab/opsaetning-af-screeningsprogram-i-danmark-foetal-og-neonatal-alloimmun-trombocytopeni

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title = "Ops{\ae}tning af screeningsprogram i Danmark for f{\o}tal og neonatal alloimmun trombocytopeni",

abstract = "Establishing a screening programme in Denmark for foetal and neonatal alloimmune thrombocytopeniaFoetal and neonatal alloimmune thrombocytopenia (FNAIT) can cause cerebral haemorrhage in newborns. FNAIT occurs in women, who do not have the thrombocyte type human platelet antigen (HPA)-1a and are carrying an HPA-1a positive foetus. Maternal antibodies can cause thrombocytopenia in the foetus or newborn. Antenatal screening for FNAIT can easily be integrated in the already existing national screening programme for rhesus immunisation. Prophylactic treatment with immunoglobulines for pregnancies at risk can prevent neonatal complications. We argue, that the WHO criteria for a screening programme for FNAIT are met.",

author = "Caroline Madsen and Prahm, {Kira Philipsen} and Cecilia Nilsson and Pedersen, {Lars Henning} and Dziegiel, {Morten Hanefeld} and Morten Hedegaard",

year = "2018",

language = "Dansk",

volume = "180",

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T1 - Opsætning af screeningsprogram i Danmark for føtal og neonatal alloimmun trombocytopeni

AU - Madsen, Caroline

AU - Prahm, Kira Philipsen

AU - Nilsson, Cecilia

AU - Pedersen, Lars Henning

AU - Dziegiel, Morten Hanefeld

AU - Hedegaard, Morten

PY - 2018

Y1 - 2018

N2 - Establishing a screening programme in Denmark for foetal and neonatal alloimmune thrombocytopeniaFoetal and neonatal alloimmune thrombocytopenia (FNAIT) can cause cerebral haemorrhage in newborns. FNAIT occurs in women, who do not have the thrombocyte type human platelet antigen (HPA)-1a and are carrying an HPA-1a positive foetus. Maternal antibodies can cause thrombocytopenia in the foetus or newborn. Antenatal screening for FNAIT can easily be integrated in the already existing national screening programme for rhesus immunisation. Prophylactic treatment with immunoglobulines for pregnancies at risk can prevent neonatal complications. We argue, that the WHO criteria for a screening programme for FNAIT are met.

AB - Establishing a screening programme in Denmark for foetal and neonatal alloimmune thrombocytopeniaFoetal and neonatal alloimmune thrombocytopenia (FNAIT) can cause cerebral haemorrhage in newborns. FNAIT occurs in women, who do not have the thrombocyte type human platelet antigen (HPA)-1a and are carrying an HPA-1a positive foetus. Maternal antibodies can cause thrombocytopenia in the foetus or newborn. Antenatal screening for FNAIT can easily be integrated in the already existing national screening programme for rhesus immunisation. Prophylactic treatment with immunoglobulines for pregnancies at risk can prevent neonatal complications. We argue, that the WHO criteria for a screening programme for FNAIT are met.

M3 - Tidsskriftartikel

C2 - 29717700

SN - 0041-5782

VL - 180

SP - 2

EP - 6

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 17

M1 - V03170211

ER -

Opsætning af screeningsprogram i Danmark for føtal og neonatal alloimmun trombocytopeni

Abstract

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