Opportunistic infections and malignancies in 231 Danish AIDS patients.

C Pedersen; J Gerstoft; P Tauris; Jens Dilling Lundgren; P C Gøtzsche; M Buhl; Yussuf Saleh Salim; K Schmidt

Opportunistic infections and malignancies in 231 Danish AIDS patients.

C Pedersen, J Gerstoft, P Tauris, Jens Dilling Lundgren, P C Gøtzsche, M Buhl, Yussuf Saleh Salim, K Schmidt

15 Citations (Scopus)

Abstract

We analysed cumulative disease frequencies in the first 231 adult Danish AIDS patients with life tables. There was a certain hierarchical pattern in the occurrence of complicating diseases. Herpes zoster, Kaposi's sarcoma and Pneumocystis carinii pneumonia were early manifestations, whereas diseases caused by cytomegalovirus and atypical mycobacteria tended to occur later in the course of AIDS. Compared with all other AIDS patients, homosexual men were more likely to develop Kaposi's sarcoma, cytomegalovirus chorioretinitis and mucocutaneous herpes simplex virus infection. The proportion of patients who developed particular diseases changed with calendar time. Most striking was a three to fourfold decrease in diseases caused by cytomegalovirus. In conclusion, the study showed that disease frequencies in patients with AIDS may vary with the patients risk behaviour and duration of AIDS, and that the frequencies of particular diseases may change with calendar time.

Translated title of the contribution	Opportunistic infections and malignancies in 231 Danish AIDS patients.
Original language	English
Journal	AIDS
Volume	4
Issue number	3
Pages (from-to)	233-238
Number of pages	6
ISSN	0269-9370
Publication status	Published - 1990

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Cite this

@article{002f0d3ef46e44aeb9eab6e4d0c607f4,

title = "Opportunistic infections and malignancies in 231 Danish AIDS patients.",

abstract = "We analysed cumulative disease frequencies in the first 231 adult Danish AIDS patients with life tables. There was a certain hierarchical pattern in the occurrence of complicating diseases. Herpes zoster, Kaposi's sarcoma and Pneumocystis carinii pneumonia were early manifestations, whereas diseases caused by cytomegalovirus and atypical mycobacteria tended to occur later in the course of AIDS. Compared with all other AIDS patients, homosexual men were more likely to develop Kaposi's sarcoma, cytomegalovirus chorioretinitis and mucocutaneous herpes simplex virus infection. The proportion of patients who developed particular diseases changed with calendar time. Most striking was a three to fourfold decrease in diseases caused by cytomegalovirus. In conclusion, the study showed that disease frequencies in patients with AIDS may vary with the patients risk behaviour and duration of AIDS, and that the frequencies of particular diseases may change with calendar time.",

author = "C Pedersen and J Gerstoft and P Tauris and Lundgren, {Jens Dilling} and G{\o}tzsche, {P C} and M Buhl and Salim, {Yussuf Saleh} and K Schmidt",

year = "1990",

language = "English",

volume = "4",

pages = "233--238",

journal = "AIDS, Supplement",

issn = "1350-2840",

publisher = "Lippincott Williams & Wilkins",

number = "3",

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TY - JOUR

T1 - Opportunistic infections and malignancies in 231 Danish AIDS patients.

AU - Pedersen, C

AU - Gerstoft, J

AU - Tauris, P

AU - Lundgren, Jens Dilling

AU - Gøtzsche, P C

AU - Buhl, M

AU - Salim, Yussuf Saleh

AU - Schmidt, K

PY - 1990

Y1 - 1990

N2 - We analysed cumulative disease frequencies in the first 231 adult Danish AIDS patients with life tables. There was a certain hierarchical pattern in the occurrence of complicating diseases. Herpes zoster, Kaposi's sarcoma and Pneumocystis carinii pneumonia were early manifestations, whereas diseases caused by cytomegalovirus and atypical mycobacteria tended to occur later in the course of AIDS. Compared with all other AIDS patients, homosexual men were more likely to develop Kaposi's sarcoma, cytomegalovirus chorioretinitis and mucocutaneous herpes simplex virus infection. The proportion of patients who developed particular diseases changed with calendar time. Most striking was a three to fourfold decrease in diseases caused by cytomegalovirus. In conclusion, the study showed that disease frequencies in patients with AIDS may vary with the patients risk behaviour and duration of AIDS, and that the frequencies of particular diseases may change with calendar time.

AB - We analysed cumulative disease frequencies in the first 231 adult Danish AIDS patients with life tables. There was a certain hierarchical pattern in the occurrence of complicating diseases. Herpes zoster, Kaposi's sarcoma and Pneumocystis carinii pneumonia were early manifestations, whereas diseases caused by cytomegalovirus and atypical mycobacteria tended to occur later in the course of AIDS. Compared with all other AIDS patients, homosexual men were more likely to develop Kaposi's sarcoma, cytomegalovirus chorioretinitis and mucocutaneous herpes simplex virus infection. The proportion of patients who developed particular diseases changed with calendar time. Most striking was a three to fourfold decrease in diseases caused by cytomegalovirus. In conclusion, the study showed that disease frequencies in patients with AIDS may vary with the patients risk behaviour and duration of AIDS, and that the frequencies of particular diseases may change with calendar time.

M3 - Journal article

SN - 1350-2840

VL - 4

SP - 233

EP - 238

JO - AIDS, Supplement

JF - AIDS, Supplement

IS - 3

ER -